RIPOR2 Antibodies

AND RIPOR2 ELISA kits, RIPOR2 Proteins

Many biological assays use antibodies to detect RIPOR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RIPOR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RIPOR2 antibodies...

We validate the specificity of these antibodies to RIPOR2 by testing them on tissues known to express RIPOR2 positively and negatively. Browse below to find the RIPOR2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RIPOR2 Infographic by Boster Bio

All RIPOR2 Products

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Specificity

Applications

Price

Anti-FAM65B RIPOR2 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A32101
100ul

RIPOR2 (NM_015864) Human Recombinant Protein

$1249
Cat # PROTQ9Y4F9
20 µg

Anti-Zebrafish Ripor2 Antibody

Zebrafish

$470
Cat # DZ41143
200 μl/vial

RIPOR2 (NM_015864) Human Over-expression Lysate

Human

$628
Cat # LS009750
100 µg

Anti-FAM65B/RIPOR2 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A32101-1
100 µg/vial

RIPOR2 Overview

Facts about Rho family-interacting cell polarization regulator 2.

RIPOR2 3D structure. Source: alphafold

Rho family-interacting cell polarization regulator 2 (RIPOR2)

Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization (PubMed:17150207, PubMed:24687993, PubMed:23241886, PubMed:24958875, PubMed:25588844, PubMed:27556504). Inhibits chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration (PubMed:23241886).

Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion (By similarity). Required for normal development of outer and inner hair cell stereocilia within the cochlea of the inner ear (By similarity).

Gene Information

Human
Gene Name:	RIPOR2
Uniprot:	Q9Y4F9
Entrez:	9750

Family

Belongs to:

RIPOR family

Alternative Names

Rho family-interacting cell polarization regulator 2

Molecular Weight

Mass (kDA):
118.519 kDA

Genomic Context


Human

Location:	6p22.3
Sequence:	6; NC_000006.12 (24804284..25042288, complement)

Tissue Specificity

Expressed in primary fetal mononuclear myoblast (PubMed:17150207). Expressed strongly in naive T lymphocytes (PubMed:27556504). Expressed weakly in activated T lymphocytes (at protein level) (PubMed:27556504). Expressed in blood cells and adult tissues of hematopoietic origin, such as the secondary lymphoid organs (PubMed:23241886). Expressed in cytotrophoblast (PubMed:9055809).

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, filopodium. Cell projection, stereocilium. Cell projection, stereocilium membrane. Apical cell membrane. Localized in the cytoplasm in cells undergoing mitosis (PubMed:17150207). Colocalized with F-actin (PubMed:17150207). Localized with RHOC within the basal domain of hair cell stereocilia, near the taper region (By similarity). Detected in punctate pattern forming a circumferential ring at the stereocilia base (By similarity). Localized to the apical stereocilia of inner and outer hair cells (By similarity). Not detected as a membrane-asso

Interacting Proteins

RHOA
RHOC

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RIPOR2

References

PMID: 9055809 by Dakour J., et al. PL48: a novel gene associated with cytotrophoblast and lineage- specific HL-60 cell differentiation.

PMID: 17150207 by Yoon S., et al. C6ORF32 is upregulated during muscle cell differentiation and induces the formation of cellular filopodia.