RIMS1 Antibodies

AND RIMS1 ELISA kits, RIMS1 Proteins

Many biological assays use antibodies to detect RIMS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RIMS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RIMS1 antibodies...

We validate the specificity of these antibodies to RIMS1 by testing them on tissues known to express RIMS1 positively and negatively. Browse below to find the RIMS1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RIMS1 Infographic by Boster Bio

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RIM1 (RIMS1) (NM_014989) Human Over-expression Lysate

Human

$960
Cat # LS022999
100 µg

RIMS1 Overview

Facts about Regulating synaptic membrane exocytosis protein 1.

RIMS1 3D structure. Source: alphafold

Regulating synaptic membrane exocytosis protein 1 (RIMS1)

Rab effector involved in exocytosis (By similarity). May act as scaffold protein that modulates neurotransmitter release at the active zone.

Essential for maintaining normal probability of neurotransmitter release and for regulating release during short- term synaptic plasticity (By similarity). Plays a role in dendrite formation by melanocytes (PubMed:23999003).

Gene Information

Human
Gene Name:	RIMS1
Uniprot:	Q86UR5
Entrez:	22999

Family

Belongs to:

No superfamily

Alternative Names

Regulating synaptic membrane exocytosis protein 1

Molecular Weight

Mass (kDA):
189.073 kDA

Genomic Context


Human

Location:	6q13
Sequence:	6; NC_000006.12 (71886703..72403145)

Tissue Specificity

Expressed in melanocytes (PubMed:23999003). Detected in brain and retina (PubMed:23999003).

Subcellular Localizations

Cell membrane; Peripheral membrane protein. Cell junction, synapse. Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein.

Interacting Proteins

ABL1

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RIMS1

References

PMID: 12659814 by Johnson S., et al. Genomic organisation and alternative splicing of human RIM1, a gene implicated in autosomal dominant cone-rod dystrophy (CORD7).

PMID: 11438518 by Coppola T., et al. Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP- 25, and synaptotagmin.