RGS4 Antibodies

AND RGS4 ELISA kits, RGS4 Proteins

Many biological assays use antibodies to detect RGS4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RGS4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RGS4 antibodies...

We validate the specificity of these antibodies to RGS4 by testing them on tissues known to express RGS4 positively and negatively. Browse below to find the RGS4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RGS4 Infographic by Boster Bio

All RGS4 Products

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Product

Figures

Specificity

Applications

Price

Anti-RGS4 Antibody

Human, Mouse, Rat

$405
Cat # A02325
100ul

Human RGS4 Recombinant Protein

SDS-PAGE

$263
Cat # PROTP49798
Starting from 10ug

RGS4 (NM_001102445) Human Over-expression Lysate

Human

$628
Cat # LS005999
100 µg

RGS4 Overview

Facts about Regulator of G-protein signaling 4.

RGS4 3D structure. Source: alphafold

Regulator of G-protein signaling 4 (RGS4)

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein.

Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein. .

Gene Information

Human
Gene Name:	RGS4
Uniprot:	P49798
Entrez:	5999

Family

Belongs to:

No superfamily

Alternative Names

DKFZp761F1924; MGC2124; MGC60244; regulator of G-protein signaling 4; regulator of G-protein signalling 4; RGP4; schizophrenia disorder 9; SCZD9

Molecular Weight

Mass (kDA):
23.256 kDA

Genomic Context


Human

Location:	1q23.3
Sequence:	1; NC_000001.11 (163068606..163076802)

Tissue Specificity

Expressed in brain and heart. Expressed in brain at protein level. Expressed in prefontal and visual cortex. Isoform 4 and isoform 5 are expressed ubiquitously. Isoform 1, isoform 2 and isoform 3 are not expressed in the cerebellum.

Diseases

Schizophrenia
Pertussis
Hypertrophy
Malignant Neoplasms
Nervousness
Mental Disorders
Bipolar Disorder
Heart Failure
Cardiac Hypertrophy
Neoplasms
Depressive Disorder
Cell Invasion

Dysequilibrium Syndrome
Neuroblastoma
Hypertensive Disease
Psychotic Disorders
Neoplasm Invasiveness
Pathologic Vasoconstriction

Pathways

Localization
Pathogenesis
Cell Proliferation
Transport
Muscle Contraction
Cell Growth
Secretion
Proteolysis
Smooth Muscle Contraction
Cell Migration
Mating
Aging
Sensitization

Vasoconstriction
Conjugation
Angiogenesis
Cognition
Regulation Of Gene Expression
Membrane Depolarization
Translation

PTMs

Phosphorylation
Palmitoylation
Glycosylation
Acetylation
Acylation

Ribosylation
Formylation
Cleavage
Oxidation
Ubiquitination

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RGS4

References

PMID: 8602223 by Druey K.M., et al. Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family.

PMID: 17707117 by Ding L., et al. Full length cloning and expression analysis of splice variants of regulator of G-protein signaling RGS4 in human and murine brain.