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- Table of Contents
Facts about Lithostathine-1-alpha.
.
Human | |
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Gene Name: | REG1A |
Uniprot: | P05451 |
Entrez: | 5967 |
Belongs to: |
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No superfamily |
ICRF; Islet cells regeneration factor; Islet of Langerhans regenerating protein; lithostathine-1-alpha; P19; pancreatic stone protein, secretory; Pancreatic thread protein; protein-X; PSP; PSPS; PSPS1; PTP; REG; Reg1A; REG-1-alpha; Regenerating islet-derived protein 1-alpha; Regenerating protein I alpha
Mass (kDA):
18.731 kDA
Human | |
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Location: | 2p12 |
Sequence: | 2; NC_000002.12 (79120488..79123409) |
In pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients.
Secreted.
PMID: 2963000 by Terazono K., et al. A novel gene activated in regenerating islets.
PMID: 2332435 by Watanabe T., et al. Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues. The reg protein, pancreatic stone protein, and pancreatic thread protein are one and the same product of the gene.