RECQL Antibodies

AND RECQL ELISA kits, RECQL Proteins

Many biological assays use antibodies to detect RECQL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RECQL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RECQL antibodies...

We validate the specificity of these antibodies to RECQL by testing them on tissues known to express RECQL positively and negatively. Browse below to find the RECQL antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RECQL Infographic by Boster Bio

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RECQ1 (RECQL) (NM_002907) Human Over-expression Lysate

Human

$628
Cat # LS005965
100 µg

RECQL Overview

Facts about ATP-dependent DNA helicase Q1.

RECQL 3D structure. Source: alphafold

ATP-dependent DNA helicase Q1 (RECQL)

DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction.

Gene Information

Human
Gene Name:	RECQL
Uniprot:	P46063
Entrez:	5965

Family

Belongs to:

helicase family

Alternative Names

DNA helicase, RecQ-like type 1; DNA-dependent ATPase Q1; EC 3.6.1; EC 3.6.4.12; RecQ protein-like (DNA helicase Q1-like); RecQ protein-like 1; RECQ1; RecQ1ATP-dependent DNA helicase Q1; RecQL1

Molecular Weight

Mass (kDA):
73.457 kDA

Genomic Context


Human

Location:	12p12.1
Sequence:	12; NC_000012.12 (21468910..21501669, complement)

Tissue Specificity

High expression in heart, lung, skeletal muscle and kidney, low expression in brain.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Werner Syndrome
Bloom Syndrome
Genomic Instability
Premature Aging Syndrome
Neoplasms
Hereditary Diseases
Rothmund-thomson Syndrome
Cell Transformation, Neoplastic
Immunologic Deficiency Syndromes
Adenocarcinoma
Pancreatic Adenocarcinoma
Diabetes Mellitus

Pancreatic Neoplasm
Cytogenetic Abnormality
Malignant Neoplasm Of Pancreas
Atherosclerosis
Chromosome Breakage
Dwarfism
Xeroderma

Interacting Proteins

KPNA2
KPNA4
PARP1

Pathways

Dna Replication
Dna Repair
Aging
Localization
Cell Cycle
Mismatch Repair
S Phase
Dna Recombination
Meiosis
Mitotic Recombination
Gene Silencing
Hypersensitivity
Telomere Maintenance

Cell Differentiation
Cell Cycle Checkpoint
Chromosome Segregation
Recombinational Repair
Mitosis
Senescence
Cell Growth

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RECQL

References

PMID: 7961977 by Puranam K.L., et al. Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNA helicase RecQ.

PMID: 7527136 by Seki M., et al. Molecular cloning of cDNA encoding human DNA helicase Q1 which has homology to Escherichia coli Rec Q helicase and localization of the gene at chromosome 12p12.