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RASSF2 Antibodies
AND RASSF2 ELISA kits, RASSF2 Proteins
Many biological assays use antibodies to detect RASSF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RASSF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RASSF2 antibodies...
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RASSF2 Infographic by Boster Bio
All RASSF2 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A04384-1
100 µg/vial
Cat # A04384-1
100 µg/vial
RASSF2 Overview
Facts about Ras association domain-containing protein 2.
Ras association domain-containing protein 2 (RASSF2)
Potential tumor suppressor. Acts as a KRAS-specific effector protein.
May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by shielding it from proteasomal degradation.
Gene Information
| Human | |
|---|---|
| Gene Name: | RASSF2 |
| Uniprot: | P50749 |
| Entrez: | 9770 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
KIAA0168DKFZp781O1747; Ras association (RalGDS/AF-6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; ras association domain-containing protein 2; RASFADIN; RASSF2
Molecular Weight
Mass (kDA):
37.79 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20p13 |
| Sequence: | 20; NC_000020.11 (4780023..4823668, complement) |
Tissue Specificity
Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
Subcellular Localizations
Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Cell Transformation, Neoplastic
- Colorectal Cancer
- Adenoma
- Colorectal Neoplasms
- Carcinogenesis
- Neoplasm Metastasis
- Malignant Neoplasm Of Stomach
- Cell Invasion
- Malignant Paraganglionic Neoplasm
- Stomach Neoplasms
Interacting Proteins
- KDM1A
- KRAS
- PRMT6
- RASSF5
- STK3
- STK4
- SUV39H1
Pathways
- Methylation
- Dna Methylation
- Cell Cycle
- Cell Growth
- Pathogenesis
- Transport
- Localization
- Cell Proliferation
- Senescence
- Nuclear Export
- Cell Cycle Arrest
- Oncogenesis
- Nuclear Import
PTMs
- Methylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RASSF2
bosterbio.com/bosterbio-gene-info-cards/RASSF2
References
PMID: 12732644 by Vos M.D., et al. RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor.
PMID: 16012945 by Akino K., et al. The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer.