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RalA-binding protein 1 Antibodies
AND RALBP1 ELISA kits, RalA-binding protein 1 Proteins
Many biological assays use antibodies to detect RalA-binding protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RalA-binding protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RalA-binding protein 1 antibodies...
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RALBP1 Infographic by Boster Bio
All RALBP1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M01403
100 μl
Cat # M01403
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01403-1
100 μg/vial
Cat # A01403-1
100 μg/vial
Human
Flow Cytometry
$515
Cat # A01403-Dyl488
100 μg/vial
Cat # A01403-Dyl488
100 μg/vial
Human
Flow Cytometry
$515
Cat # A01403-Dyl550
100 μg/vial
Cat # A01403-Dyl550
100 μg/vial
Human
Flow Cytometry, WB
$370
Cat # M01403-2
100 μg/vial
Cat # M01403-2
100 μg/vial
Dog, Human, Mouse, Rat
Flow Cytometry, IP, IF, WB
$523
Cat # M01403-3
100 µl
Cat # M01403-3
100 µl
Human, Mouse, Rat
IP, IF, IHC, WB
$523
Cat # M01403-1
100 µl
Cat # M01403-1
100 µl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01403-4
100 μg/vial
Cat # M01403-4
100 μg/vial
RALBP1 Overview
Facts about RalA-binding protein 1.
RalA-binding protein 1 (RALBP1)
Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the significant ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes.
Can catalyze transport of glutathione conjugates and xenobiotics, and may add to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complicated during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
Gene Information
| Human | |
|---|---|
| Gene Name: | RALBP1 |
| Uniprot: | Q15311 |
| Entrez: | 10928 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Dinitrophenyl S-glutathione ATPase; ralA binding protein 1; ralA-binding protein 1,76 kDa Ral-interacting protein; RalBP1; Ral-interacting protein 1; RIP; RIP1; RLIP1; RLIP76DNP-SG ATPase
Molecular Weight
Mass (kDA):
76.063 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18p11.22 |
| Sequence: | 18; NC_000018.10 (9475513..9538114) |
Subcellular Localizations
Membrane; Peripheral membrane protein.
Diseases
- Malignant Neoplasms
- Neoplasms
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Lung
- Non-small Cell Lung Carcinoma
- Lung Neoplasms
- Carcinoma
- Pancreatic Neoplasm
- Malignant Paraganglionic Neoplasm
- Small Cell Carcinoma Of Lung
- Inflammation
- Tumor Angiogenesis
Interacting Proteins
- C1orf216
- CBY1
- CCDC6
- CCL20
- CEP57
- CREBZF
- DLG1
- GPS2
- KANK2
- MSANTD4
Pathways
- Transport
- Endocytosis
- Cell Death
- Drug Resistance
- Angiogenesis
- Cell Proliferation
- Mitosis
- Localization
- Cell Migration
- Necroptosis
- Receptor-mediated Endocytosis
- Cell Cycle
- Exocytosis
PTMs
- Phosphorylation
- Ubiquitination
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RALBP1
bosterbio.com/bosterbio-gene-info-cards/RALBP1
References
PMID: 7673236 by Jullien-Flores V., et al. Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity.
PMID: 10924126 by Awasthi S., et al. Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin.