RAI1 Antibodies

AND RAI1 ELISA kits, RAI1 Proteins

Many biological assays use antibodies to detect RAI1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAI1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAI1 antibodies...

We validate the specificity of these antibodies to RAI1 by testing them on tissues known to express RAI1 positively and negatively. Browse below to find the RAI1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RAI1 Infographic by Boster Bio

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RAI1 Overview

Facts about Retinoic acid-induced protein 1.

RAI1 3D structure. Source: alphafold

Retinoic acid-induced protein 1 (RAI1)

Transcriptional regulator of the circadian clock Parts: CLOCK, ARNTL/BMAL1, ARNTL2/BMAL2, PER1/3, CRY1/2, NR1D1/2 and RORA/C.
Positively regulates the transcriptional activity of CLOCK a core part of the circadian clock.

Regulates transcription through chromatin remodeling by interacting with other proteins in chromatin as well as proteins in the basic transcriptional machinery. Might be important for embryonic and postnatal development.

Gene Information

Human
Gene Name:	RAI1
Uniprot:	Q7Z5J4
Entrez:	10743

Family

Belongs to:

No superfamily

Alternative Names

KIAA1820DKFZP434A139; MGC12824; retinoic acid induced 1; retinoic acid-induced protein 1; SMCR; Smith-Magenis syndrome chromosome region; SMSDKFZp434A139

Molecular Weight

Mass (kDA):
203.352 kDA

Genomic Context


Human

Location:	17p11.2
Sequence:	17; NC_000017.11 (17681376..17811453)

Tissue Specificity

Expressed in all tissues examined with higher expression in the heart and brain. No expression was seen in the corpus callosum of the brain.

Subcellular Localizations

Cytoplasm. Nucleus. In neurons, localized to neurites.

Diseases

Smith-magenis Syndrome
Haploinsufficiency
Craniofacial Abnormalities
Sleep Disorders
Congenital Abnormality
Duplication 17p11.2 Syndrome
Obesity
Autistic Disorder
Loss Of Chromosome 17
Dwarfism
Chromosomal Deletion
Schizophrenia

Mutation, Out-of-frame
Multiple Congenital Anomalies
Developmental Delay (disorder)
Virus Diseases
Ataxia
Mental Disorders

Interacting Proteins

PIN1

Pathways

Circadian Rhythm
Localization
Immune Response
Rna Interference
Innate Immune Response
Ribosome Biogenesis
Secretion
Social Behavior
Rna Processing
Viral Replication
Transport
Cell Activation
Heterochromatin Assembly

Gene Silencing
Regulation Of Gene Expression
Ossification
B Cell Activation
Type I Interferon Production
Embryo Development
Sensitization

PTMs

Phosphorylation

Cleavage

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAI1

References

PMID: 11404004 by Seranski P., et al. RAI1 is a novel polyglutamine encoding gene that is deleted in Smith- Magenis syndrome patients.

PMID: 12837267 by Toulouse A., et al. Molecular cloning and characterization of human RAI1, a gene associated with schizophrenia.