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, No Gclids
Racgap1 Antibodies
AND Racgap1 ELISA kits, Racgap1 Proteins
Many biological assays use antibodies to detect Racgap1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Racgap1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Racgap1 antibodies...
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Racgap1 Infographic by Boster Bio
All Racgap1 Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A03018S387
100ul
Cat # A03018S387
100ul
Human, Monkey, Mouse, Rat
IHC, WB
$523
Cat # M03018
100 µl
Cat # M03018
100 µl
Racgap1 Overview
Facts about Rac GTPase-activating protein 1.
Rac GTPase-activating protein 1 (Racgap1)
Component of the centralspindlin complex that functions as a microtubule-dependent and Rho-mediated signaling needed for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis.
Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms aside from regulating Rac GTPase activity. Also included in the regulation of growth-related procedures in adipocytes and myoblasts.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Racgap1 |
| Uniprot: | Q9WVM1 |
| Entrez: | 26934 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
GTPase activating protein; HsCYK-4; ID-GAP; KIAA1478; Male germ cell RacGap; MgcRacGAP; MgcRacGAPrac GTPase-activating protein 1; Rac GTPase activating protein 1; RACGAP1
Molecular Weight
Mass (kDA):
70.158 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 15|15 F1 |
| Sequence: | 15; |
Tissue Specificity
Highly expressed in testis, thymus and spleen and weakly expressed in brain, heart, skeletal muscle and kidney. In testis, expression is restricted to germ cells with the highest levels of expression found in spermatocytes. Not detected in adult liver. Also expressed in fetal liver and in several hematopoietic cell lines.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Neoplasm Of Breast
- Liver Neoplasms
- Neoplasm Metastasis
- Liver Carcinoma
- Carcinogenesis
- Cell Invasion
- Cell Transformation, Neoplastic
- Leukemia
- Intraepithelial Neoplasia
- Embryonal Carcinoma
Pathways
- Localization
- Cell Division
- Cell Migration
- Cytokinesis
- Cell Cycle
- Cell Proliferation
- Mitosis
- Cellular Process
- Immune Response
- Metaphase
- Spermatogenesis
- Anaphase
- Asymmetric Cell Division
PTMs
- Acetylation
- Isopeptide bond
Research Areas
- Core ESC-Like Genes
- Signal Transduction
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Racgap1
bosterbio.com/bosterbio-gene-info-cards/Racgap1
References
PMID: 10235109 by Wooltorton E.J., et al. Identification and characterization of a transcript for a novel Rac GTPase-activating protein in terminally differentiating 3T3-L1 adipocytes.
PMID: 10979956 by Kawashima T., et al. MgcRacGAP is involved in the control of growth and differentiation of hematopoietic cells.