RAB38 Antibodies

AND RAB38 ELISA kits, RAB38 Proteins

Many biological assays use antibodies to detect RAB38, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAB38 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAB38 antibodies...

We validate the specificity of these antibodies to RAB38 by testing them on tissues known to express RAB38 positively and negatively. Browse below to find the RAB38 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: PRKD3

RAB38 Infographic by Boster Bio

All RAB38 Products

Product

Figures

Specificity

Applications

Price

1 Q&As

Human, Mouse, Rat

ELISA, WB

$335
Cat # A05500
100ul

RAB38 (NM_022337) Human Over-expression Lysate

Human

$628
Cat # LS023682
100 µg

RAB38 Overview

Facts about Ras-related protein Rab-38.

RAB38 3D structure. Source: alphafold

Ras-related protein Rab-38 (RAB38)

May be involved in melanosomal transportation and docking. Involved in the proper sorting of TYRP1.

Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which likely is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.

Gene Information

Human
Gene Name:	RAB38
Uniprot:	P57729
Entrez:	23682

Family

Belongs to:

small GTPase superfamily

Alternative Names

Melanoma antigen NY-MEL-1; NY-MEL-1; RAB38, member RAS oncogene family; Rab-related GTP-binding protein; ras-related protein Rab-38; rrGTPbp

Molecular Weight

Mass (kDA):
23.712 kDA

Genomic Context


Human

Location:	11q14.2
Sequence:	11; NC_000011.10 (87809490..88175504, complement)

Tissue Specificity

Expressed in melanocytes.

Subcellular Localizations

Cell membrane; Lipid-anchor; Cytoplasmic side. Melanosome. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Melanosome membrane. Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991).

Diseases

Hermanski-pudlak Syndrome
Albinism, Oculocutaneous
Albinism
Melanoma
Malignant Neoplasms
Neoplasms
Hemorrhage
Malignant Paraganglionic Neoplasm
Hereditary Diseases
Bleeding Tendency
Lung Diseases
Hypopigmentation Disorder

Pigmentation Disorders
Platelet Storage Pool Deficiency
Hypertensive Disease
Autoimmunity
Cholangiocarcinoma
Neoplasm Metastasis
Microphthalmos

Pathways

Transport
Pigmentation
Vesicle Transport
Localization
Surfactant Homeostasis
Melanocyte Differentiation
Pathogenesis
Secretion
Osteoclast Differentiation
Eye Pigmentation
Phagosome Maturation
Immune Response
Proteolysis

Platelet Aggregation
Sensitization
Translation
Melanosome Transport
Exocytosis
Chromosome Condensation
Endosomal Transport

PTMs

Farnesylation
Prenylation
Cleavage

Methylation
Geranylgeranylation
Palmitoylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAB38

References

PMID: 10910072 by Jaeger D., et al. Serological cloning of a melanocyte rab guanosine 5'-triphosphate- binding protein and a chromosome condensation protein from a melanoma complementary DNA library.

PMID: 12643545 by Basrur V., et al. Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.