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- Table of Contents
Facts about Ras-related protein Rab-1A.
RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and to the cell surface, and plays a part in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane.
Human | |
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Gene Name: | RAB1A |
Uniprot: | P62820 |
Entrez: | 5861 |
Belongs to: |
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small GTPase superfamily |
DKFZp564B163; member RAS oncogene family; RAB1A, member RAS oncogene family; ras-related protein Rab-1A
Mass (kDA):
22.678 kDA
Human | |
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Location: | 2p14 |
Sequence: | 2; NC_000002.12 (65086854..65130301, complement) |
Golgi apparatus. Endoplasmic reticulum. Early endosome. Cytoplasm, cytosol. Membrane. Melanosome. Alternates between membrane-associated and cytosolic forms.
PMID: 2501306 by Zahraoui A., et al. The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.
PMID: 1902553 by Bailly E., et al. Phosphorylation of two small GTP-binding proteins of the Rab family by p34cdc2.