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Rab18 Antibodies
AND Rab18 ELISA kits, Rab18 Proteins
Many biological assays use antibodies to detect Rab18, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Rab18 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Rab18 antibodies...
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Rab18 Overview
Facts about Ras-related protein Rab-18.
Ras-related protein Rab-18 (Rab18)
Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes.
Plays a key role in eye and brain development and neurodegeneration (By similarity). .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Rab18 |
| Uniprot: | P35293 |
| Entrez: | 19330 |
Family
| Belongs to: |
|---|
| small GTPase superfamily |
Alternative Names
RAB18 small GTPase; RAB18, member RAS oncogene family; RAB18LI1; ras-related protein Rab-18
Molecular Weight
Mass (kDA):
23.035 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 18 A1|18 4.53 cM |
| Sequence: | 18; |
Tissue Specificity
Expression is high in the brain, moderate in the pituitary, and low in the liver. Detected in all tissues.
Diseases
- Physiological Stress
- Pituitary Diseases
- Dehydration
- Neoplasms
- Hypopigmentation-immunodeficiency Disease
- Diabetes Mellitus
- Inflammation
- Hypogonadism
- Lymphohistiocytosis, Hemophagocytic
- Cholangiocarcinoma
- Optic Atrophy
- Growth Hormone-secreting Pituitary Adenoma
Pathways
- Germination
- Transport
- Localization
- Seed Germination
- Cold Acclimation
- Secretory Pathway
- Stomatal Closure
- Secretion
- Seedling Development
- Seed Development
- Drought Tolerance
- Senescence
- Regulated Secretory Pathway
PTMs
- Phosphorylation
- Acetylation
- Sumoylation
- Farnesylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Rab18
bosterbio.com/bosterbio-gene-info-cards/Rab18
References
PMID: 7706395 by Luetcke A., et al. Cloning and subcellular localization of novel rab proteins reveals polarized and cell type-specific expression.
PMID: 7916717 by Yu H., et al. Gene cloning and characterization of a GTP-binding Rab protein from mouse pituitary AtT-20 cells.