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- Table of Contents
, No Gclids
PROCR Antibodies
AND PROCR ELISA kits, PROCR Proteins
Many biological assays use antibodies to detect PROCR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PROCR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PROCR antibodies...
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PROCR Infographic by Boster Bio
All PROCR Products
Product
Figures
Specificity
Applications
Price
Mouse
ELISA
$499
Cat # EK1439
96 wells/kit, with removable strips.
Cat # EK1439
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK0957
96 wells/kit, with removable strips.
Cat # EK0957
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ0957
For 5 plates, 96 wells each
Cat # EZ0957
For 5 plates, 96 wells each
PROCR Overview
Facts about Endothelial protein C receptor.
Endothelial protein C receptor (PROCR)
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
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Gene Information
| Human | |
|---|---|
| Gene Name: | PROCR |
| Uniprot: | Q9UNN8 |
| Entrez: | 10544 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
APC receptor; CCCA; CCD41; CCD41centrosome-associated protein; CD201 antigen; CD201; centrocyclin; Endothelial cell protein C receptor; endothelial protein C receptor; EPCR; EPCRMGC23024; PROCR; protein C receptor, endothelial
Molecular Weight
Mass (kDA):
26.671 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20q11.22 |
| Sequence: | 20; NC_000020.11 (35172072..35215989) |
Tissue Specificity
Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney.
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Inflammation
- Thrombosis
- Systemic Infection
- Malignant Neoplasms
- Severe Sepsis
- Thromboembolism
- Venous Thrombosis
- Tissue Adhesions
- Neoplasms
- Venous Thromboembolism
- Inflammatory Response
- Thrombophilia
- Lupus Erythematosus, Systemic
Interacting Proteins
- F2R
Pathways
- Coagulation
- Blood Coagulation
- Inflammatory Response
- Cell Proliferation
- Cell Migration
- Chemotaxis
- Wound Healing
- Hemostasis
- Angiogenesis
- Cell Adhesion
- Pathogenesis
- Fibrinolysis
- Secretion
PTMs
- Cleavage
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PROCR
bosterbio.com/bosterbio-gene-info-cards/PROCR
References
PMID: 7929370 by Fukudome K., et al. Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor.
PMID: 10397730 by Simmonds R.E., et al. Structural and functional implications of the intron/exon organization of the human endothelial cell protein C/activated protein C receptor (EPCR) gene: comparison with the structure of CD1/major histocompatibility complex alpha1 and alpha2 domains.