PPP2R2B Antibodies

AND PPP2R2B ELISA kits, PPP2R2B Proteins

Many biological assays use antibodies to detect PPP2R2B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP2R2B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP2R2B antibodies...

We validate the specificity of these antibodies to PPP2R2B by testing them on tissues known to express PPP2R2B positively and negatively. Browse below to find the PPP2R2B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPP2R2B Infographic by Boster Bio

All PPP2R2B Products

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Anti-PPP2R2B Antibody

3 Q&As

Human, Mouse, Rat

$360
Cat # A05805
100 µl

PPP2R2B (NM_004576) Human Over-expression Lysate

Human

$960
Cat # LS005521
100 µg

PPP2R2B Overview

Facts about Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform.

PPP2R2B 3D structure. Source: alphafold

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PPP2R2B)

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is needed to promote proapoptotic activity (By similarity).

Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity). .

Gene Information

Human
Gene Name:	PPP2R2B
Uniprot:	Q00005
Entrez:	5521

Family

Belongs to:

phosphatase 2A regulatory subunit B family

Alternative Names

B55BETA; FLJ95686; MGC24888; PP2A subunit B isoform B55-beta; PP2A subunit B isoform beta; PP2A subunit B isoform PR55-beta; PP2A subunit B isoform R2-beta; PP2A, subunit B, B-beta isoform; PP2AB55BETA; PP2ABBETA; PP2APR55B; PP2APR55BETA; PR2AB55BETA; PR2ABBETA; PR2APR55BETA; PR52B; PR55BETA; PR55-BETA; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform; protein phosphatase 2, regulatory subunit B, beta; SCA12; serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, betaisoform;

Molecular Weight

Mass (kDA):
51.71 kDA

Genomic Context


Human

Location:	5q32
Sequence:	5; NC_000005.10 (146580742..147081520, complement)

Tissue Specificity

Brain.

Subcellular Localizations

[Isoform 1]: Cytoplasm. Cytoplasm, cytoskeleton. Membrane.; [Isoform 2]: Cytoplasm. Mitochondrion. Mitochondrion outer membrane. Under basal conditions, localizes to both cytosolic and mitochondrial compartments. Relocalizes from the cytosolic to the mitochondrial compartment during apoptosis. Its targeting to the outer mitochondrial membrane (OMM) involves an association with import receptors of the TOM complex and is required to promote proapoptotic activity (By similarity).