Protocadherin alpha-4 Antibodies

AND Pcdha4 ELISA kits, Protocadherin alpha-4 Proteins

Many biological assays use antibodies to detect Protocadherin alpha-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protocadherin alpha-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protocadherin alpha-4 antibodies...

We validate the specificity of these antibodies to Protocadherin alpha-4 by testing them on tissues known to express Pcdha4 positively and negatively. Browse below to find the Pcdha4 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Pcdha4 Infographic by Boster Bio

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Pcdha4 Overview

Facts about Protocadherin alpha-4.

Protocadherin alpha-4 (Pcdha4)

Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination (Probable). Thereby, it's involved in the establishment and maintenance of specific neuronal connections in the brain (PubMed:27161523).

Gene Information

Mouse
Gene Name:	Pcdha4
Uniprot:	O88689
Entrez:	12936

Family

Belongs to:

No superfamily

Alternative Names

CNR1; CNRN1; CRNR1; KIAA0345-like 10; MGC138307; MGC142169; ortholog of mouse CNR1; PCDHA4; PCDH-ALPHA4; PCDH-alpha-4; Protocadherin alpha 4; protocadherin alpha-4

Molecular Weight

Mass (kDA):
103.143 kDA

Genomic Context


Mouse

Location:	18\|18 B2-B3
Sequence:	18;

Tissue Specificity

Detected in brain throughout embryonic development. Detected in adult brain, in particular in cerebellum and forebrain.

Diseases

Tissue Adhesions
Nervousness
Sclerosis
Primary Lateral Sclerosis
Neurodegenerative Disorders
Schizophrenia
Amyotrophic Lateral Sclerosis
Degenerative Polyarthritis
Parkinson Disease
Mental Disorders

Nicotine Dependence
Diseases In Twins
Drug Use Disorder
Depressive Disorder
Tobacco Use Disorder

Pathways

Localization
Cell Adhesion
Tissue Development
Gene Conversion
Brain Development
Proteolysis
Spermatogenesis

Myelination

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Pcdha4

References

PMID: 9655502 by Kohmura N., et al. Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.

PMID: 11230163 by Wu Q., et al. Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.