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- Table of Contents
3 Citations 16 Q&As
3 Citations 17 Q&As
1 Citations
Facts about Paxillin.
Human | |
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Gene Name: | PXN |
Uniprot: | P49023 |
Entrez: | 5829 |
Belongs to: |
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paxillin family |
FLJ16691; Paxillin; PXN
Mass (kDA):
64.505 kDA
Human | |
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Location: | 12q24.23 |
Sequence: | 12; NC_000012.12 (120210439..120265771, complement) |
Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, cell cortex. Colocalizes with integrins at the cell periphery. Colocalize with PXN to membrane ruffles and the leading edge of migrating cells (PubMed:23128389).
PMID: 7534286 by Salgia R., et al. Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.
PMID: 9054445 by Mazaki Y., et al. Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins.
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