Peroxidasin homolog Antibodies

AND PXDN ELISA kits, Peroxidasin homolog Proteins

Many biological assays use antibodies to detect Peroxidasin homolog, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Peroxidasin homolog in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Peroxidasin homolog antibodies...

We validate the specificity of these antibodies to Peroxidasin homolog by testing them on tissues known to express PXDN positively and negatively. Browse below to find the PXDN antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: ALMS1

PXDN Infographic by Boster Bio

All PXDN Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Zebrafish PXDN Antibody

Zebrafish

$470
Cat # DZ06456
200 μl/vial

Anti-human peroxidasin homolog isoform X1 Antibody

Human, Mouse, Rat

IHC-P, WB

$470
Cat # DZ33984
200 μl/vial

PXDN (NM_012293) Human Over-expression Lysate

Human

$960
Cat # LS007837
100 µg

PXDN Overview

Facts about Peroxidasin homolog.

PXDN 3D structure. Source: alphafold

Peroxidasin homolog (PXDN)

Displays low peroxidase activity and is very likely to take part in H(2)O(2) metabolism and peroxidative reactions in the cardiovascular system. Plays a role in extracellular matrix formation.

Gene Information

Human
Gene Name:	PXDN
Uniprot:	Q92626
Entrez:	7837

Family

Belongs to:

peroxidase family

Alternative Names

peroxidasin homolog (Drosophila)

Molecular Weight

Mass (kDA):
165.275 kDA

Genomic Context


Human

Location:	2p25.3
Sequence:	2; NC_000002.12 (1631887..1744852, complement)

Tissue Specificity

Expressed at higher levels in heart, lung, ovary, spleen, intestine and placenta, and at lower levels in liver, colon, pancreas, kidney, thymus, skeletal muscle and prostate. Expressed in tumors such as melanoma, breast cancer, ovarian cancer and glioblastoma. A shorter form probably lacking the signal sequence is found in testis and in EB1 cells undergoing p53/TP53-dependent apoptosis.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix. Enriched in the peritubular space of fibrotic kidneys.

Diseases

Neoplasms
Neoplasm Metastasis
Chromosomal Duplication
Schizophrenia
Tissue Adhesions
Melanoma
Glioma
Endometrial Polyp
Irido-corneal Dysgenesis
Leukemia, Myelocytic, Acute
Metastatic Malignant Neoplasm To Brain
Tumor Angiogenesis

Endometritis
Malignant Neoplasms
Flushing
Puerperal Disorders
Myeloid Leukemia
Loss Of Chromosome 5q

Pathways

Cell Adhesion
Transport
Glycosylation
Localization
Methylation
Swimming
Cell Cycle
Cell Motility
Amino Acid Transport

Regulation Of Cell Motility
Cell Growth
Angiogenesis
Protein Stabilization

PTMs

Phosphorylation
Demethylation

Glycosylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PXDN

References

PMID: 10441517 by Horikoshi N., et al. Isolation of differentially expressed cDNAs from p53-dependent apoptotic cells: activation of the human homologue of the Drosophila peroxidasin gene.

PMID: 11103812 by Mitchell M.S., et al. A novel melanoma gene (MG50) encoding the interleukin 1 receptor antagonist and six epitopes recognized by human cytolytic T lymphocytes.