PWP1 Antibodies

AND PWP1 ELISA kits, PWP1 Proteins

Many biological assays use antibodies to detect PWP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PWP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PWP1 antibodies...

We validate the specificity of these antibodies to PWP1 by testing them on tissues known to express PWP1 positively and negatively. Browse below to find the PWP1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PWP1 Infographic by Boster Bio

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Anti-PWP1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M10720
100 μl/vial

PWP1 Overview

Facts about Periodic tryptophan protein 1 homolog.

PWP1 3D structure. Source: alphafold

Periodic tryptophan protein 1 homolog (PWP1)

Chromatin-associated factor that regulates transcription (PubMed:29065309). Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription (PubMed:29065309).

Regulates the epigenetic status of rDNA (PubMed:29065309). .

Gene Information

Human
Gene Name:	PWP1
Uniprot:	Q13610
Entrez:	11137

Family

Belongs to:

WD repeat PWP1 family

Alternative Names

IEF-SSP-9502; Keratinocyte protein IEF SSP 9502; nuclear phosphoprotein similar to S. cerevisiae PWP1; periodic tryptophan protein 1 homolog; PWP1 homolog (S. cerevisiae)

Molecular Weight

Mass (kDA):
55.828 kDA

Genomic Context


Human

Location:	12q23.3
Sequence:	12; NC_000012.12 (107685732..107713162)

Tissue Specificity

High levels seen in the placenta, skeletal muscle, kidney and pancreas while lower levels were seen in the heart, brain and lung.

Subcellular Localizations

Nucleus. Nucleus, nucleolus. Chromosome. Associates with chromatin regions of rDNA.

Diseases

Adenocarcinoma
Pancreatic Adenocarcinoma
Vaccinia
Malignant Neoplasms
Heat Stress Disorders
Pancreatic Neoplasm
Porokeratosis, Disseminated Superficial Actinic

Malignant Neoplasm Of Pancreas

Pathways

Cell Cycle
Keratinization
Mitosis
Cell Growth
Interphase
Meiosis

Localization

PTMs

Sumoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PWP1

References

PMID: 7828893 by Honore B., et al. Cloning of a cDNA encoding a novel human nuclear phosphoprotein belonging to the WD-40 family.

PMID: 29065309 by Liu Y., et al. PWP1 Mediates Nutrient-Dependent Growth Control through Nucleolar Regulation of Ribosomal Gene Expression.