PTPRA Antibodies

AND PTPRA ELISA kits, PTPRA Proteins

Many biological assays use antibodies to detect PTPRA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTPRA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTPRA antibodies...

We validate the specificity of these antibodies to PTPRA by testing them on tissues known to express PTPRA positively and negatively. Browse below to find the PTPRA antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTPRA Infographic by Boster Bio

All PTPRA Products

Product

Figures

Specificity

Applications

Price

Anti-PTP Alpha (I792) PTPRA Antibody

Human, Mouse, Rat

$405
Cat # A03280
100ul

Anti-Phospho-PT alpha (Y798) PTPRA Antibody

Human, Monkey, Mouse, Rat

ELISA, WB

$380
Cat # A03280Y798
100ul

PTP alpha (PTPRA) (NM_002836) Human Recombinant Protein

$1249
Cat # PROTP18433
20 µg

PTP alpha (PTPRA) (NM_002836) Human Over-expression Lysate

Human

$628
Cat # LS005786
100 µg

PTPRA Overview

Facts about Receptor-type tyrosine-protein phosphatase alpha.

PTPRA 3D structure. Source: alphafold

Receptor-type tyrosine-protein phosphatase alpha (PTPRA)

Gene Information

Human
Gene Name:	PTPRA
Uniprot:	P18433
Entrez:	5786

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

EC 3.1.3.48; HEPTP; HLPR; LRP; LRPHPTPalpha; protein tyrosine phosphatase, receptor type, A; Protein-tyrosine phosphatase alpha; PTP alpha; PTPAreceptor type, alpha polypeptide; PTPase-alpha; PTPLCA-related phosphatase; PTPRA; PTPRL2; receptor-type tyrosine-protein phosphatase alpha; RPTPA; R-PTP-alpha; tyrosine phosphatase alpha

Molecular Weight

Mass (kDA):
90.719 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (2864195..3038669)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion. Localizes to focal adhesion sites following integrin engagement.

Diseases

Posttransfusion Purpura
Tissue Adhesions
Malignant Neoplasms
Neoplasms
Insulin Resistance
Carcinoma
Diabetes Mellitus
Nervousness
Mammary Neoplasms
Liver Carcinoma
Malignant Neoplasm Of Breast
Diabetes Mellitus, Non-insulin-dependent
Cell Transformation, Neoplastic

Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Obesity
Malignant Tumor Of Colon
Pheochromocytoma
Insulin Sensitivity
Stomach Neoplasms

Interacting Proteins

EGFR
Fyn
GRB2
SRC

Pathways

Cell Adhesion
Cell Growth
Localization
Cell Migration
Secretion
Cell Activation
Cell Motility
Cell Differentiation
Pathogenesis
Innervation
Mammary Gland Development
Axon Guidance
Cell Proliferation

Gland Development
Glycosylation
Regeneration
Aging
Cell Cycle
Transdifferentiation
Gastrulation

PTMs

Phosphorylation
Dephosphorylation
Cleavage
Oxidation
Acetylation

Biotinylation
Nitration
Reduction
Glycosylation
Palmitoylation

Research Areas

GPCR
Protein Phosphatase
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTPRA

References

PMID: 2169617 by Kaplan R., et al. Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain.

PMID: 2170109 by Krueger N.X., et al. Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.