PTP4A2 Antibodies

AND PTP4A2 ELISA kits, PTP4A2 Proteins

Many biological assays use antibodies to detect PTP4A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTP4A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTP4A2 antibodies...

We validate the specificity of these antibodies to PTP4A2 by testing them on tissues known to express PTP4A2 positively and negatively. Browse below to find the PTP4A2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTP4A2 Infographic by Boster Bio

All PTP4A2 Products

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Product

Figures

Specificity

Applications

Price

Anti-PTP4A2 Antibody Picoband®

6 Q&As

Human, Rat

Flow Cytometry, IHC, WB

$370
Cat # PB9740
100 μg/vial

PTP4A2 (NM_080391) Human Recombinant Protein

$813
Cat # PROTQ12974
20 µg

PTP4A2 (NM_080391) Human Over-expression Lysate

Human

$628
Cat # LS008073
100 µg

PTP4A2 Overview

Facts about Protein tyrosine phosphatase type IVA 2.

PTP4A2 3D structure. Source: alphafold

Protein tyrosine phosphatase type IVA 2 (PTP4A2)

Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors.

Inhibits geranylgeranyl transferase type II action by blocking the association between RABGGTA and RABGGTB. .

Gene Information

Human
Gene Name:	PTP4A2
Uniprot:	Q12974
Entrez:	8073

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

EC 3.1.3.48; HH13; HH7-2; HU-PP-1; HU-PP-1HH13; OV-1; OV-1PTP4A; PRL2; PRL-2; PRL-2HH7-2; PRL2protein tyrosine phosphatase IVA; protein tyrosine phosphatase IVA2; protein tyrosine phosphatase type IVA 2; protein tyrosine phosphatase type IVA, member 2; Protein-tyrosine phosphatase 4a2; Protein-tyrosine phosphatase of regenerating liver 2; PTP(CAAXII); PTP4A2; PTPCAAX2; PTPCAAX2phosphatase of regenerating liver 2; ptp-IV1a; ptp-IV1b

Molecular Weight

Mass (kDA):
19.127 kDA

Genomic Context


Human

Location:	1p35.2
Sequence:	1; NC_000001.11 (31906421..31938368, complement)

Tissue Specificity

Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue.

Subcellular Localizations

Cell membrane. Early endosome. Cytoplasm.

Diseases

Neoplasm Metastasis
Neoplasms
Malignant Neoplasms
Cell Invasion
Posttransfusion Purpura
Neoplasm Invasiveness
Carcinoma
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Breast
Mammary Neoplasms
Colonic Neoplasms
Colorectal Cancer
Cell Transformation, Neoplastic

Lymphatic Metastasis
Metastatic Malignant Neoplasm To The Lymph Node
Myeloid Leukemia
Adenocarcinoma
Malignant Neoplasm Of Lung
Leukemia, Myelocytic, Acute
Lung Neoplasms

Pathways

Prenylation
Cell Proliferation
Localization
Cell Migration
Cell Adhesion
Pathogenesis
Histone Modification
Cell Division
Cellular Localization
Cell Motility

Cell Cycle
Cell Growth
Rna Interference
Tissue Homeostasis
Chromatin Remodeling

PTMs

Prenylation
Farnesylation

Phosphorylation
Dephosphorylation

Geranylgeranylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTP4A2

References

PMID: 8529999 by Montagna M., et al. A 100-kb physical and transcriptional map around the EDH17B2 gene: identification of three novel genes and a pseudogene of a human homologue of the rat PRL-1 tyrosine phosphatase.

PMID: 9018080 by Cates C.A., et al. Prenylation of oncogenic human PTP(CAAX) protein tyrosine phosphatases.