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- Table of Contents
Facts about Prostate tumor-overexpressed gene 1 protein.
Promotes cell proliferation. .
Human | |
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Gene Name: | PTOV1 |
Uniprot: | Q86YD1 |
Entrez: | 53635 |
Belongs to: |
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Mediator complex subunit 25 family |
ACID2; Activator interaction domain-containing protein 2; DKFZp586I111; MGC71475; prostate tumor overexpressed 1; prostate tumor overexpressed gene 1; PTOV-1
Mass (kDA):
46.869 kDA
Human | |
---|---|
Location: | 19q13.33 |
Sequence: | 19; NC_000019.10 (49848554..49860744) |
Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine.
Cell membrane. Cytoplasm, perinuclear region. Nucleus. Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts.
PMID: 11313889 by Benedit P., et al. PTOV1, a novel protein overexpressed in prostate cancer containing a new class of protein homology blocks.
PMID: 14657022 by Mittler G., et al. A novel docking site on Mediator is critical for activation by VP16 in mammalian cells.