PTGFR Antibodies

AND PTGFR ELISA kits, PTGFR Proteins

Many biological assays use antibodies to detect PTGFR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTGFR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTGFR antibodies...

We validate the specificity of these antibodies to PTGFR by testing them on tissues known to express PTGFR positively and negatively. Browse below to find the PTGFR antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTGFR Infographic by Boster Bio

All PTGFR Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PGF2α Receptor (FP) Ptgfr Antibody

13 Q&As

Mouse, Rat

ELISA, WB

$613
Cat # A04716
100µg

Anti-PF2R PTGFR Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A04716-1
100ul

Prostaglandin F2 alpha Receptor (PTGFR) (NM_000959) Human Over-expression Lysate

Human

$628
Cat # LS005737
100 µg

PTGFR Overview

Facts about Prostaglandin F2-alpha receptor.

PTGFR 3D structure. Source: alphafold

Prostaglandin F2-alpha receptor (PTGFR)

Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.

Gene Information

Human
Gene Name:	PTGFR
Uniprot:	P43088
Entrez:	5737

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

FP; MGC120498; MGC46203; PGF receptor; PGF2 alpha receptor; PGF2-alpha Receptor; prostaglandin F receptor (FP); prostaglandin F2 alpha receptor; prostaglandin F2-alpha receptor; prostaglandin receptor (2-alpha); Prostanoid FP receptor; PTGFR

Molecular Weight

Mass (kDA):
40.055 kDA

Genomic Context


Human

Location:	1p31.1
Sequence:	1; NC_000001.11 (78490974..78540701)

Tissue Specificity

Eye.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Premature Obstetric Labor
Malignant Neoplasms
Neoplasms
Dysequilibrium Syndrome
Tissue Adhesions
Neoplasm Metastasis
Fracture Of First Cervical Vertebra
Extravasation
Malignant Neoplasm Of Breast
Glaucoma, Open-angle
Endometrial Polyp
Infertility
Abnormal Coordination

Inflammatory Response
Intestinal Diseases
Carcinogenesis
Asthma
Mammary Neoplasms
Crushing Sensation
Celiac Disease

Pathways

Parturition
Luteolysis
Localization
Ovulation
Pathogenesis
Cell Adhesion
Cell Activation
Endothelial Cell Activation
Reproductive Process
Cell Development
Immune Response
Neutrophil Extravasation

Inflammatory Response
Maternal Behavior
Cell Growth
Diestrus
Innervation
Luteinization

PTMs

Disulfide bond

Glycoprotein

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTGFR

References

PMID: 8300593 by Abramovitz M., et al. Cloning and expression of a cDNA for the human prostanoid FP receptor.

PMID: 9341156 by Kunapuli P., et al. Functional characterization of the ocular prostaglandin f2alpha (PGF2alpha) receptor. Activation by the isoprostane, 12-iso- PGF2alpha.