PTGDR2 Antibodies

AND PTGDR2 ELISA kits, PTGDR2 Proteins

Many biological assays use antibodies to detect PTGDR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTGDR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTGDR2 antibodies...

We validate the specificity of these antibodies to PTGDR2 by testing them on tissues known to express PTGDR2 positively and negatively. Browse below to find the PTGDR2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTGDR2 Infographic by Boster Bio

All PTGDR2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CD294 PTGDR2 Antibody

4 Q&As

Human, Mouse

IHC, WB

$399
Cat # A12856
100μl

Anti-CRTH2 PTGDR2 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A12856-1
0.1 mg

GPR44 (PTGDR2) (NM_004778) Human Over-expression Lysate

Human

$628
Cat # LS011251
100 µg

PTGDR2 Overview

Facts about Prostaglandin D2 receptor 2.

PTGDR2 3D structure. Source: alphafold

Prostaglandin D2 receptor 2 (PTGDR2)

Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein.

Receptor activation may result in pertussis toxin- sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling can be implicated in mediating PTGDR2 effects.

Gene Information

Human
Gene Name:	PTGDR2
Uniprot:	Q9Y5Y4
Entrez:	11251

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

CD294 antigen; CD294; Chemoattractant receptor-homologous molecule expressed on Th2 cells; CRTH2; CRTH-2; CRTH2chemoattractant receptor homologous molecule expressed on T helper type 2 cells; DL1R; DP2; G protein-coupled receptor 44; GPR44; PGD2R; PTGDR2; putative G-protein coupled receptor 44

Molecular Weight

Mass (kDA):
43.268 kDA

Genomic Context


Human

Location:	11q12.2
Sequence:	11; NC_000011.10 (60850933..60855950, complement)

Tissue Specificity

Widespread expression. High expression in stomach, small intestine, heart and thymus. Intermediate expression in colon, spinal cord and peripheral blood and low expression in brain, skeletal muscle and spleen. Expressed also on Th2- and Tc2- type cells, eosinophils and basophils.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Internalized receptors colocalized with RAB11A.

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTGDR2

References

PMID: 10036181 by Marchese A., et al. Discovery of three novel orphan G-protein-coupled receptors.

PMID: 9973380 by Nagata K., et al. Selective expression of a novel surface molecule by human Th2 cells in vivo.