PSMD8 Antibodies

AND PSMD8 ELISA kits, PSMD8 Proteins

Many biological assays use antibodies to detect PSMD8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PSMD8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PSMD8 antibodies...

We validate the specificity of these antibodies to PSMD8 by testing them on tissues known to express PSMD8 positively and negatively. Browse below to find the PSMD8 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PSMD8 Infographic by Boster Bio

All PSMD8 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PSMD8 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A12465
100ul

PSMD8 (NM_002812) Human Recombinant Protein

$813
Cat # PROTP48556
20 µg

Anti-PSMD8 Antibody Picoband®

Human, Mouse, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A12465-1
100 μg/vial

PSMD8 (NM_002812) Human Over-expression Lysate

Human

$628
Cat # LS005714
100 µg

PSMD8 Overview

Facts about 26S proteasome non-ATPase regulatory subunit 8.

PSMD8 3D structure. Source: alphafold

26S proteasome non-ATPase regulatory subunit 8 (PSMD8)

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.

Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. .

Gene Information

Human
Gene Name:	PSMD8
Uniprot:	P48556
Entrez:	5714

Family

Belongs to:

proteasome subunit S14 family

Alternative Names

26S proteasome non-ATPase regulatory subunit 8; 26S proteasome regulatory subunit p31; HIP6,26S proteasome regulatory subunit S14; HYPF; MGC1660; Nin1p; p3126S proteasome regulatory subunit RPN12; proteasome (prosome, macropain) 26S subunit, non-ATPase, 8; Rpn12; S14

Molecular Weight

Mass (kDA):
39.612 kDA

Genomic Context


Human

Location:	19q13.2
Sequence:	19; NC_000019.10 (38374550..38383824)

Diseases

Malignant Neoplasms
Stage I Non-small Cell Lung Cancer
Coronary Heart Disease
Lung Neoplasms
Non-neoplastic Disorder
Non-small Cell Lung Carcinoma
Malignant Neoplasm Of Breast
Angina Pectoris
Atherosclerosis
Coronary Artery Disease
Malignant Neoplasm Of Lung

Neoplasms
Coronary Arteriosclerosis
Mammary Neoplasms
Acute Coronary Syndrome
Chronic Stable Angina
Hyperplasia

Pathways

Proteolysis
Transport
Fertilization
Platelet Activation
Exocytosis

PTMs

Cleavage

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PSMD8

References

PMID: 7621825 by Kominami K., et al. Nin1p, a regulatory subunit of the 26S proteasome, is necessary for activation of Cdc28p kinase of Saccharomyces cerevisiae.

PMID: 1317798 by Kanayama H.O., et al. Demonstration that a human 26S proteolytic complex consists of a proteasome and multiple associated protein components and hydrolyzes ATP and ubiquitin-ligated proteins by closely linked mechanisms.