PSMA3 Antibodies

Proteasome subunit alpha type-3 (PSMA3)

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles.

Connected with two 19S regulatory particles, forms the 26S proteasome and so participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by eliminating misfolded or damaged proteins which could impair cellular functions, and by eliminating proteins whose functions are no longer required.

Gene Information

Human
Gene Name:	PSMA3
Uniprot:	P25788
Entrez:	5684

Family

Belongs to:
peptidase T1A family

Alternative Names

EC 3.4.25.1; HC8MGC32631; Macropain subunit C8; MGC12306; Multicatalytic endopeptidase complex subunit C8; proteasome (prosome, macropain) subunit, alpha type, 3; Proteasome component C8; proteasome subunit alpha type-3; proteasome subunit C8; PSC3; PSC8

Molecular Weight

Mass (kDA):
28.433 kDA

Genomic Context

Human
Location:	14q23.1
Sequence:	14; NC_000014.9 (58244805..58272009)

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

• Neoplasm Metastasis
• Neoplasms
• Liver Diseases
• Monosomy
• Melanoma
• Hepatitis B
• Neoplasm Invasiveness
• Carcinoma
• Carcinoma, Pancreatic Ductal
• Malignant Neoplasms
• Pancreatic Neoplasm
• Pituitary Diseases
• Malignant Neoplasm Of Pancreas

• Cell Invasion
• Adenocarcinoma
• Pancreatic Ductal Adenocarcinoma
• Chronic Fatigue Syndrome
• Liver Carcinoma
• Hepatitis
• Tissue Adhesions

Pathways

• Cell Migration
• Programmed Cell Death
• Cell Motility
• Cell Death
• Fibrinolysis
• Mitosis
• Proteolysis
• Pathogenesis

• Glycolysis
• Secretion

PTMs

• Phosphorylation

Research Areas

• Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PSMA3

Best Uses of the PSMA3 Marker in Boster Bio Antibodies

Have you ever wondered how companies like Boster Bio develop PSMA3 antibodies? In this article, we'll explore the PSMA3 Marker and its application in Boster Bio antibodies. This research uses mice and rabbit to produce antibodies against PSMA3.

Boster Bio uses PSMA3 Marker

A highly specific, high-affinity antibody that recognizes PSMA3 is available from Boster Bio. These antibodies have been cited extensively in the literature over the last 25 years and are trusted by the research community. Boster antibodies have been validated for use in Western Blotting, Immunohistochemistry, and ELISA applications. Read on to find out more about this highly specific antibody. Also available from Boster Bio are reagents that can be used in conjunction with other antibodies to identify PSMA3 in a variety of cell types.

Boster Bio uses mouse and rabbit to develop PSMA3 antibodies

As part of its Picoband(tm) antibody library, Boster Bio's anti-Proteasome 20S alpha 3 antibody has been validated for PSMA3 in human tissues, cell lines and ELISA. This high-affinity antibody reacts with human, rabbit and mouse PSMA3 protein. Boster Bio antibodies are also validated for immunohistochemistry, Western Blotting and immunocytochemistry.