Trypsin-1 Antibodies

AND PRSS1 ELISA kits, Trypsin-1 Proteins

Many biological assays use antibodies to detect Trypsin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Trypsin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Trypsin-1 antibodies...

We validate the specificity of these antibodies to Trypsin-1 by testing them on tissues known to express PRSS1 positively and negatively. Browse below to find the PRSS1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRSS1 Infographic by Boster Bio

All PRSS1 Products

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Specificity

Applications

Price

Anti-Trypsin-1 PRSS1 Antibody

7 Q&As

Human

$399
Cat # A01637
100μl

Anti-Trypsin-1 PRSS1 Antibody

Human, Mouse

IHC, WB

$405
Cat # A01637-1
100ul

Trypsin (PRSS1) (NM_002769) Human Over-expression Lysate

Human

$628
Cat # LS005644
100 µg

PRSS1 Overview

Facts about Trypsin-1.

PRSS1 3D structure. Source: alphafold

Trypsin-1 (PRSS1)

Has Action against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec.
The single-chain form is more active than the two- chain form against all of these substrates.

Gene Information

Human
Gene Name:	PRSS1
Uniprot:	P07477
Entrez:	5644

Family

Belongs to:

peptidase S1 family

Alternative Names

Beta-trypsin; Cationic trypsinogen; digestive zymogen; DKFZp779A0837; EC 3.4.21; EC 3.4.21.4; FLJ57296; MGC120175; MGC149362; nonfunctional trypsin 1; protease, serine, 1 (trypsin 1); PRSS1; PTRYI; Serine protease 1; TRP1; TRY1beta-trypsin; TRY4; Trygn16; TRYP1; Trypsin 1; Trypsin I; trypsin-1; Trypsinogen 1; trypsinogen A

Molecular Weight

Mass (kDA):
26.558 kDA

Genomic Context


Human

Location:	7q34
Sequence:	7; NC_000007.14 (142740235..142753076)

Subcellular Localizations

Secreted, extracellular space.

Diseases

Pancreatitis
Pancreatitis, Chronic
Malignant Neoplasms
Fibrosis
Malignant Neoplasm Of Pancreas
Cystic Fibrosis
Pancreatic Neoplasm
Acute Pancreatitis
Diabetes Mellitus
Pain
Pancreatitis, Alcoholic
Adenocarcinoma

Pancreatic Diseases
Neoplasms
Inflammation
Acute Recurrent Pancreatitis
Pancreatitis Acute On Chronic
Hereditary Diseases

Pathways

Pathogenesis
Trypsinogen Activation
Secretion
Autolysis
Inflammatory Response
Gene Conversion
Transport
Localization
Cell Death
Intein-mediated Protein Splicing
Programmed Cell Death
Fertilization
Immune Response

Proteolysis
Pigmentation
Cell Division
Flight
Reverse Transcription
Translation
Cell Cycle

PTMs

Cleavage
Phosphorylation

Deamination
Glycosylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRSS1

References

PMID: 3011602 by Emi M., et al. Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens.

PMID: 8650574 by Rowen L., et al. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus.