Peripherin-2 Antibodies

AND PRPH2 ELISA kits, Peripherin-2 Proteins

Many biological assays use antibodies to detect Peripherin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Peripherin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Peripherin-2 antibodies...

We validate the specificity of these antibodies to Peripherin-2 by testing them on tissues known to express PRPH2 positively and negatively. Browse below to find the PRPH2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRPH2 Infographic by Boster Bio

All PRPH2 Products

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Specificity

Applications

Price

PRPH2 (NM_000322) Human Recombinant Protein

$813
Cat # PROTP23942
20 µg

PRPH2 (NM_000322) Human Over-expression Lysate

Human

$628
Cat # LS005961
100 µg

PRPH2 Overview

Facts about Peripherin-2.

PRPH2 3D structure. Source: alphafold

Peripherin-2 (PRPH2)

May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the upkeep of the curvature of the rim. It's essential for disk morphogenesis.

Gene Information

Human
Gene Name:	PRPH2
Uniprot:	P23942
Entrez:	5961

Family

Belongs to:

PRPH2/ROM1 family

Alternative Names

AOFMD; AVMD; CACD2; CACD2peripherin 2, homolog of mouse; DS; peripherin 2 (retinal degeneration, slow); Peripherin 2; peripherin-2; PRPH2; PRPHperipherin, photoreceptor type; rd2; RDS; Retinal degeneration slow protein; retinal degeneration, slow; retinal peripherin; RP7; Tetraspanin-22; TSPAN22; tspan-22; TSPAN22retinal degeneration, slow (retinitis pigmentosa 7)

Molecular Weight

Mass (kDA):
39.186 kDA

Genomic Context


Human

Location:	6p21.1
Sequence:	6; NC_000006.12 (42694509..42723039, complement)

Tissue Specificity

Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.

Subcellular Localizations

Membrane; Multi-pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment.

Diseases

Retinal Degeneration
Retinitis Pigmentosa
Age Related Macular Degeneration
Dystrophy
Blind Vision
Retinal Dystrophies
Atrophy
Choroidal Sclerosis
Vitelliform Macular Dystrophy
Abnormal Degeneration

Macule
Stargardt's Disease
Retinal Diseases
Choroid Diseases

Pathways

Cell Death
Pathogenesis
Programmed Cell Death
Gene Silencing
Aging
Localization
Neuroprotection
Locomotion
Mating

Rna Interference
Hormone Secretion
Autophagy
Secretion

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRPH2

References

PMID: 1679750 by Travis G.H., et al. The human retinal degeneration slow (RDS) gene: chromosome assignment and structure of the mRNA.

PMID: 8956033 by Keen T.J., et al. Mutations and polymorphisms in the human peripherin-RDS gene and their involvement in inherited retinal degeneration.