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- Table of Contents
Facts about Pre-mRNA-processing factor 40 homolog B.
Human | |
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Gene Name: | PRPF40B |
Uniprot: | Q6NWY9 |
Entrez: | 25766 |
Belongs to: |
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PRPF40 family |
Pre-mRNA-processing factor 40 homolog B
Mass (kDA):
99.358 kDA
Human | |
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Location: | 12q13.12 |
Sequence: | 12; NC_000012.12 (49622717..49645129) |
Expressed in the striatum and cortex of the brain (at protein level). Highly expressed in testis, fetal kidney and fetal brain. Moderately expressed in pancreas, skeletal muscle, placenta, brain and heart. Weakly expressed in colon, ileum, ovary, prostate, spleen, kidney and fetal lung.
Nucleus speckle.
PMID: 9700202 by Faber P.W., et al. Huntingtin interacts with a family of WW domain proteins.
PMID: 10958656 by Passani L.A., et al. Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis.