PRPF31 Antibodies

AND PRPF31 ELISA kits, PRPF31 Proteins

Many biological assays use antibodies to detect PRPF31, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRPF31 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRPF31 antibodies...

We validate the specificity of these antibodies to PRPF31 by testing them on tissues known to express PRPF31 positively and negatively. Browse below to find the PRPF31 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRPF31 Infographic by Boster Bio

All PRPF31 Products

Product

Figures

Specificity

Applications

Price

Anti-PRP31 Antibody

3 Q&As

Human, Mouse

ELISA, WB

$335
Cat # A30534
100ul

Anti-PRPF31 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A03137
100ul

PRPF31 (NM_015629) Human Recombinant Protein

$1249
Cat # PROTQ8WWY3
20 µg

Anti-PRPF31 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IF, ICC, WB

$370
Cat # M03137
100 μl/vial

PRPF31 (NM_015629) Human Over-expression Lysate

Human

$960
Cat # LS026121
100 µg

Anti-PRPF31 Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A03137-1
100 µg/vial

PRPF31 Overview

Facts about U4/U6 small nuclear ribonucleoprotein Prp31.

PRPF31 3D structure. Source: alphafold

U4/U6 small nuclear ribonucleoprotein Prp31 (PRPF31)

Involved in pre-mRNA splicing as part of the spliceosome (PubMed:11867543, PubMed:28781166). Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (PubMed:11867543).

Gene Information

Human
Gene Name:	PRPF31
Uniprot:	Q8WWY3
Entrez:	26121

Family

Belongs to:

PRP31 family

Alternative Names

DKFZp566J153; hPrp31; NY-BR-99; Pre-mRNA-processing factor 31; Protein 61K; PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae); PRP31 pre-mRNA processing factor 31 homolog (yeast); PRP31RP11; Serologically defined breast cancer antigen NY-BR-99; U4/U6 small nuclear ribonucleoprotein Prp31; U4/U6 snRNP 61 kDa protein

Molecular Weight

Mass (kDA):
55.456 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (54115706..54131719)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Nucleus. Nucleus speckle. Nucleus, Cajal body. Predominantly found in speckles and in Cajal bodies.

Diseases

Retinitis Pigmentosa
Retinal Degeneration
Haploinsufficiency
Blind Vision
Hereditary Diseases
Night Blindness
Cytogenetic Abnormality
Retinal Diseases
Dystrophy
De Novo Mutation
Abnormal Degeneration

Disorder Of Eye
Retinal Dystrophies
Amaurosis
Brain Ischemia
Stenosis
Hypoxia

Pathways

Rna Splicing
Mrna Splicing
Pathogenesis
Localization
Protein Phosphorylation
Transport
Cell Proliferation
Circadian Rhythm
Nuclear Transport

Methylation
Cell Death
Rrna Processing
Nuclear Import

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRPF31

References

PMID: 11867543 by Makarova O.V., et al. Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6.U5 tri-snRNP formation and pre-mRNA splicing.

PMID: 12747765 by Scanlan M.J., et al. Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression.