PRC1 Antibodies

AND PRC1 ELISA kits, PRC1 Proteins

Many biological assays use antibodies to detect PRC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRC1 antibodies...

We validate the specificity of these antibodies to PRC1 by testing them on tissues known to express PRC1 positively and negatively. Browse below to find the PRC1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRC1 Infographic by Boster Bio

All PRC1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PRC1 Antibody Picoband®

4 Q&As

Human

$370
Cat # PB9814
100 μg/vial

Anti-PRC1 Rabbit Monoclonal Antibody

17 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M00160
100 μl

Anti-PRC1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A00160
0.1 mg

Anti-PRC1 Antibody (Phospho-Thr481)

Human

ELISA, WB

$380
Cat # A00160T481
100ul

PRC1 (NM_003981) Human Over-expression Lysate

Human

$628
Cat # LS009055
100 µg

PRC1 Overview

Facts about Protein regulator of cytokinesis 1.

PRC1 3D structure. Source: alphafold

Protein regulator of cytokinesis 1 (PRC1)

Key regulator of cytokinesis which cross-links antiparrallel microtubules at a mean distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and effective cytokinesis.

Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 into the spindle.

Gene Information

Human
Gene Name:	PRC1
Uniprot:	O43663
Entrez:	9055

Family

Belongs to:

MAP65/ASE1 family

Alternative Names

anaphase spindle elongation 1 homolog; ASE1; MGC1671; MGC3669; protein regulating cytokinesis 1; protein regulator of cytokinesis 1

Molecular Weight

Mass (kDA):
71.607 kDA

Genomic Context


Human

Location:	15q26.1
Sequence:	15; NC_000015.10 (90966038..90994576, complement)

Tissue Specificity

Overexpressed in bladder cancer cells (PubMed:17409436).

Subcellular Localizations

Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Midbody. Colocalized with KIF20B in the nucleus of bladder carcinoma cells at the interphase. Colocalized with KIF20B in bladder carcinoma cells at prophase, metaphase, early anaphase, at the midzone in late anaphase and at the contractile ring in telophase (PubMed:17409436). Predominantly localized to the nucleus of interphase cells. During mitosis becomes associated with the mitotic spindle poles and localizes with the cell midbody during cytokinesis.