PPP3R1 Antibodies

AND PPP3R1 ELISA kits, PPP3R1 Proteins

Many biological assays use antibodies to detect PPP3R1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP3R1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP3R1 antibodies...

We validate the specificity of these antibodies to PPP3R1 by testing them on tissues known to express PPP3R1 positively and negatively. Browse below to find the PPP3R1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: PPP3R2

PPP3R1 Infographic by Boster Bio

All PPP3R1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Calcineurin Alpha Ppp3r1 Antibody (Monoclonal, CN-A1)

6 Q&As

Bovine, Human, Mouse, Rat

IHC, WB

$370
Cat # MA1008
100 μg/vial

Anti-Calcineurin subunit B type 1 PPP3R1 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A06469
100ul

Human Calcineurin B Recombinant Protein

SDS-PAGE

$250
Cat # PROTP63098
Starting from 20ug

Anti-PPP3R1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A06469-1
100 µg/vial

PPP3R1 Overview

Facts about Calcineurin subunit B type 1.

PPP3R1 3D structure. Source: alphafold

Calcineurin subunit B type 1 (PPP3R1)

Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.

Gene Information

Human
Gene Name:	PPP3R1
Uniprot:	P63098
Entrez:	5534

Family

Belongs to:

calcineurin regulatory subunit family

Alternative Names

Calcineurin B; calcineurin subunit B type 1; CALNB1; CNA2; Cnb1; MCIP1; PP2B beta 1; PPP3R1; Protein phosphatase 2B regulatory subunit 1; protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform(calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform(calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform; Protein phosphatase 3 regulatory subunit B alpha isoform 1; protein phosphatase 3, regulatory subunit B, alpha; type I (19kDa)

Molecular Weight

Mass (kDA):
19.3 kDA

Genomic Context


Human

Location:	2p14
Sequence:	2; NC_000002.12 (68178857..68252532, complement)

Subcellular Localizations

Cytoplasm, cytosol. Cell membrane. Cell membrane, sarcolemma. Cell membrane; Lipid-anchor. Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocyte hypertrophy.

Diseases

Hereditary Diseases
Diabetes Mellitus
Heart Diseases
Hypertrophy
Coronary Heart Disease
Dementia
Cardiac Hypertrophy
Carcinoma
Left Ventricular Hypertrophy
Endometriosis, Site Unspecified
Neoplasms
Cerebrovascular Accident

Nervousness
Exhaustion
Attention Deficit Hyperactivity Disorder
Ventricular Dysfunction, Left
Osteoporosis
Dysequilibrium Syndrome

Interacting Proteins

MAP3K5
PPP3CA
PPP3CC

Pathways

Protein Phosphorylation
Cell Proliferation
Insulin Secretion
Cell Development
Dense Core Granule Biogenesis
Intracellular Signal Transduction
Localization
Demethylation
Cell Maturation

Notch Signaling Pathway
Cell Division
Cell Growth
Secretion

PTMs

Phosphorylation

Dephosphorylation

Demethylation

Research Areas

Protein Phosphatase
Signal Transduction
Wnt Signaling Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP3R1

References

PMID: 2558868 by Guerini D., et al. Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase.

PMID: 12809556 by Genesca L., et al. Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life.