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- Table of Contents
Facts about RelA-associated inhibitor.
Also inhibits p53/TP53 feature, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and so suppressing the subsequent activation of apoptosis. .
Human | |
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Gene Name: | PPP1R13L |
Uniprot: | Q8WUF5 |
Entrez: | 10848 |
Belongs to: |
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iASPP family |
IASPPinhibitor of apoptosis stimulating protein of p53; Inhibitor of ASPP protein; NFkB-interacting protein 1; NKIP1; PPP1R13BL; PPP1R13B-like protein; Protein iASPP; protein phosphatase 1, regulatory (inhibitor) subunit 13 like; protein phosphatase 1, regulatory subunit 13 like; RAINFkB interacting protein 1; relA-associated inhibitor
Mass (kDA):
89.091 kDA
Human | |
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Location: | 19q13.32 |
Sequence: | 19; NC_000019.10 (45379634..45406361, complement) |
Highly expressed in heart, placenta and prostate. Weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte.
Cytoplasm. Nucleus. Predominantly cytoplasmic but also nuclear.
PMID: 15489900 by Slee E.A., et al. The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization.
PMID: 10336463 by Yang J.-P., et al. Identification of a novel inhibitor of nuclear factor-kappaB, RelA- associated inhibitor.