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Platelet basic protein Antibodies
AND PPBP ELISA kits, Platelet basic protein Proteins
Many biological assays use antibodies to detect Platelet basic protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Platelet basic protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Platelet basic protein antibodies...
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PPBP Infographic by Boster Bio
All PPBP Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$750
Cat # EK0729
96 wells/kit, with removable strips.
Cat # EK0729
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ0729
For 5 plates, 96 wells each
Cat # EZ0729
For 5 plates, 96 wells each
Mouse
ELISA
$499
Cat # EK0730
96 wells/kit, with removable strips.
Cat # EK0730
96 wells/kit, with removable strips.
Rat
ELISA
$499
Cat # EK0731
96 wells/kit, with removable strips.
Cat # EK0731
96 wells/kit, with removable strips.
Rat
$250
Cat # PROTQ99ME0
2ug, 10ug, 1mg
Cat # PROTQ99ME0
2ug, 10ug, 1mg
Mouse
Cell Culture
$77
Cat # PROTQ9EQI5
5ug,20ug,100ug
Cat # PROTQ9EQI5
5ug,20ug,100ug
Mouse
Cell Culture
$77
Cat # PROTQ9EQI5-1
5ug,20ug,100ug
Cat # PROTQ9EQI5-1
5ug,20ug,100ug
PPBP Overview
Facts about Platelet basic protein.
Platelet basic protein (PPBP)
LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. Additionally, it stimulates the formation and secretion of plasminogen activator by human synovial cells.
NAP-2 is a ligand for both CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and many potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules.
Gene Information
| Human | |
|---|---|
| Gene Name: | PPBP |
| Uniprot: | P02775 |
| Entrez: | 5473 |
Family
| Belongs to: |
|---|
| intercrine alpha (chemokine CxC) family |
Alternative Names
Beta-TG; connective tissue-activating peptide III; CTAP III; CTAP3CTAP-III; CTAPIII; CXC chemokine ligand 7; C-X-C motif chemokine 7; CXCL7; CXCL7b-TG1; LA-PF4; LDGFTC1; Leukocyte-derived growth factor; low-affinity platelet factor IV; Macrophage-derived growth factor; MDGFTC2; NAP2; NAP-2; NAP-2-L1; neutrophil-activating peptide 2; neutrophil-activating peptide-2; PBPTHBGB; platelet basic protein; PPBP; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7); SCAR10; SCYB7beta-thromboglobulin; small inducible cytokine B7; small inducible cytokine subfamily B, member 7; Small-inducible c
Molecular Weight
Mass (kDA):
13.894 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q13.3 |
| Sequence: | 4; NC_000004.12 (73986439..73988190, complement) |
Subcellular Localizations
Secreted.
Diseases
- Inflammation
- Endocarditis
- Melanoma
- Infective Disorder
- Bacteremia
- Infarction
- Staphylococcal Infections
- Ischemia
- Bacterial Endocarditis
- Arterial Occlusion
- Occlusion, Middle Cerebral Artery
- Cerebral Artery Occlusion
Interacting Proteins
- CCL5
- CXCL9
Pathways
- Chemotaxis
- Pathogenesis
- Neuroprotection
- Secretion
- Neutrophil Chemotaxis
- Platelet Activation
- Neutrophil Activation
- Cell Activation
- Inflammatory Response
- Neutrophil Degranulation
- Cell Death
- Exocytosis
- Proteolysis
PTMs
- Cleavage
- Phosphorylation
- Formylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPBP
bosterbio.com/bosterbio-gene-info-cards/PPBP
References
PMID: 2713489 by Wenger R.H., et al. Cloning of cDNA coding for connective tissue activating peptide III from a human platelet-derived lambda gt11 expression library.
PMID: 1826003 by Majumdar S., et al. Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4.