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POU5F1 Antibodies
AND POU5F1 ELISA kits, POU5F1 Proteins
Many biological assays use antibodies to detect POU5F1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POU5F1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POU5F1 antibodies...
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POU5F1 Infographic by Boster Bio
All POU5F1 Products
Product
Figures
Specificity
Applications
Price
Anti-Oct4 POU5F1 Rabbit Monoclonal Antibody
2 Citations 3 Q&As
Human, Mouse
IP, IF, IHC, ICC, WB
$370
Cat # M00174
100 μl
Cat # M00174
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1005
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1005
1 kit, containing one 96-well plate and all necessary reagents
Anti-Oct4/POU5F1 Antibody Picoband®
1 Citations 1 Q&As
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00174-1
100 μg/vial
Cat # A00174-1
100 μg/vial
Human, Mouse, Rat
IF, WB
$523
Cat # M00174-1
100 µl
Cat # M00174-1
100 µl
POU5F1 Overview
Facts about POU domain, class 5, transcription factor 1.
POU domain, class 5, transcription factor 1 (POU5F1)
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Types a trimeric complex with SOX2 on DNA and controls the expression of a variety of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206.
Critical for early embryogenesis and for embryonic stem cell pluripotency. .
Gene Information
| Human | |
|---|---|
| Gene Name: | POU5F1 |
| Uniprot: | Q01860 |
| Entrez: | 5460 |
Family
| Belongs to: |
|---|
| POU transcription factor family |
Alternative Names
class 5, transcription factor 1; MGC22487; Oct-3; OCT3Oct4; Oct-4; Octamer-binding protein 3; otc-4; OTF3POU domain class 5, transcription factor 1; OTF4; POU class 5 homeobox 1; POU-type homeodomain-containing DNA-binding protein
Molecular Weight
Mass (kDA):
38.571 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p21.33 |
| Sequence: | 6; NC_000006.12 (31164337..31170682, complement) |
Tissue Specificity
Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
Subcellular Localizations
Cytoplasm. Nucleus. Expressed in a diffuse and slightly punctuate pattern. Colocalizes with MAPK8 and MAPK9 in the nucleus.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Teratoma
- Idiopathic Pneumonia Syndrome
- Embryonal Carcinoma
- Malignant Paraganglionic Neoplasm
- Cell Transformation, Neoplastic
- Testicular Neoplasms
- Germ Cell Tumor
- Leukemia
- Neoplasm Metastasis
Interacting Proteins
- CTCF
- FOXD3
- Hmgb1
- MBD3
- SOX2
- WWP2
Pathways
- Methylation
- Cell Differentiation
- Dna Methylation
- Cell Proliferation
- Cell Cycle
- Localization
- Gastrulation
- Rna Interference
- Demethylation
- Translation
- Stem Cell Differentiation
- Regeneration
- Cell Development
PTMs
- Methylation
- Phosphorylation
- Demethylation
- Acetylation
- Cleavage
- Deacetylation
Research Areas
- Cellular Markers
- Chromatin Research
- Glia Markers
- Neuroscience
- Oligodendrocyte Cell Markers
- Pancreatic Stem Cell Markers
- Stem Cell Markers
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POU5F1
bosterbio.com/bosterbio-gene-info-cards/POU5F1
References
PMID: 1408763 by Takeda J., et al. Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues.
PMID: 20604894 by Stuart P.E., et al. Comparison of MHC class I risk haplotypes in Thai and Caucasian psoriatics shows locus heterogeneity at PSORS1.
5 Publications of Boster POU5F1 Antibodies & ELISA Kits
- PubMed ID: 10.3892/mmr.2014.2367, Knockdown of OCT4 suppresses the growth and invasion of pancreatic cancer cells ...
- PubMed ID: 10.1186/s13287-019-1544-y, IGF-1 enhances BMSC viability, migration, and anti-apoptosis in myocardial infar...
- PubMed ID: 10.1155/2021/8493431, LncRNA LINC00662 Exerts an Oncogenic Effect on Osteosarcoma by the miR-16-5p/ITP...
- PubMed ID: 26616638, Isolation and morphological characterization of ovine amniotic fluid mesenchymal...
- PubMed ID: 25017645, Knockdown of OCT4 suppresses the growth and invasion of pancreatic cancer cells ...
*More publications can be found for each product on its corresponding product page