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- Table of Contents
Facts about POU domain, class 2, transcription factor 1.
In the event of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby allowing the transcription of the viral immediate early genes. .
Human | |
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Gene Name: | POU2F1 |
Uniprot: | P14859 |
Entrez: | 5451 |
Belongs to: |
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POU transcription factor family |
FLJ42836; NF-A1; Oct-1; OCT1class 2, transcription factor 1; OTF1; POU class 2 homeobox 1; POU domain class 2, transcription factor 1; POU2F1
Mass (kDA):
76.472 kDA
Human | |
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Location: | 1q24.2 |
Sequence: | 1; NC_000001.11 (167220878..167427345) |
Ubiquitous. Isoform 2 is lymphocyte-specific.
Nucleus.
PMID: 2905684 by Sturm R.A., et al. The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.
PMID: 12663137 by Luchina N.N., et al. Human Oct-1L isoform has tissue-specific expression pattern similar to Oct-2.