POMP Antibodies

AND POMP ELISA kits, POMP Proteins

Many biological assays use antibodies to detect POMP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POMP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POMP antibodies...

We validate the specificity of these antibodies to POMP by testing them on tissues known to express POMP positively and negatively. Browse below to find the POMP antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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POMP Infographic by Boster Bio

All POMP Products

Product

Figures

Specificity

Applications

Price

Anti-Proteasome maturation protein POMP Antibody

Human

$405
Cat # A04837
100ul

HSPC014 (POMP) (NM_015932) Human Recombinant Protein

$1249
Cat # PROTQ9Y244
20 µg

HSPC014 (POMP) (NM_015932) Human Over-expression Lysate

Human

$628
Cat # LS051371
100 µg

Anti-POMP Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A04837-1
100 µg/vial

POMP Overview

Facts about Proteasome maturation protein.

POMP 3D structure. Source: alphafold

Proteasome maturation protein (POMP)

Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation.

Mediates the institution of 20S preproteasome with the endoplasmic reticulum. .

Gene Information

Human
Gene Name:	POMP
Uniprot:	Q9Y244
Entrez:	51371

Family

Belongs to:

POMP/UMP1 family

Alternative Names

C13orf12; chromosome 13 open reading frame 12; HSPC014; hUMP1; PNAS-110; proteasome maturation protein; proteassemblin; Protein UMP1 homolog; UMP12510048O06Rik; Voltage-gated K channel beta subunit 4.1; voltage-gated potassium channel beta subunit 4.1

Molecular Weight

Mass (kDA):
15.789 kDA

Genomic Context


Human

Location:	13q12.3
Sequence:	13; NC_000013.11 (28659130..28678959)

Tissue Specificity

Strongly expressed from the basal layer to the granular layer of healthy epidermis, whereas in KLICK patients there is a gradual decrease of expression toward the granular layer.

Subcellular Localizations

Cytoplasm, cytosol. Nucleus. Microsome membrane.

Diseases

Leukemia
Ulcer
Helicobacter Infections
Leukemia, Myelocytic, Acute
Gastroesophageal Reflux Disease
Hemorrhage
Peptic Ulcer
Malignant Neoplasms
Neoplasms
Acute Leukemia
Gastric Ulcer
Myeloid Leukemia
Lymphoid Leukemia

Duodenal Ulcer
Acute Promyelocytic Leukemia
Dyspepsia
Carcinoma
Helicobacter Pylori Infection
Nervousness
Polyps

Interacting Proteins

PSMB1
PSMB3
PSMB5
PSMB7
PSMB9

Pathways

Proteasome Assembly
Proteolysis
Localization
Reflex
Coagulation
Induction Of Apoptosis
Aging
Immune Response
Humoral Immune Response

Spermatogenesis
Senescence
Cell Cycle
Hemostasis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POMP

References

PMID: 20226437 by Dahlqvist J., et al. A single-nucleotide deletion in the POMP 5' UTR causes a transcriptional switch and altered epidermal proteasome distribution in KLICK genodermatosis.

PMID: 10926487 by Witt E., et al. Characterisation of the newly identified human Ump1 homologue POMP and analysis of LMP7(beta 5i) incorporation into 20 S proteasomes.