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- Table of Contents
Facts about POC1 centriolar protein homolog A.
Acts in concert with POC1B to ensure centriole ethics and proper mitotic spindle formation. .
Human | |
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Gene Name: | POC1A |
Uniprot: | Q8NBT0 |
Entrez: | 25886 |
Belongs to: |
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WD repeat POC1 family |
DKFZp434C245; MGC131902; PIX2; POC1 centriolar protein homolog A (Chlamydomonas); POC1 centriolar protein homolog A; WD repeat domain 51A; WD repeat-containing protein 51A; WDR51A
Mass (kDA):
45.009 kDA
Human | |
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Location: | 3p21.2 |
Sequence: | 3; NC_000003.12 (52075226..52154423, complement) |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole. Component of both mother and daughter centrioles.
PMID: 18068700 by Hames R.S., et al. Pix1 and Pix2 are novel WD40 microtubule-associated proteins that colocalize with mitochondria in Xenopus germ plasm and centrosomes in human cells.
PMID: 20008567 by Pearson C.G., et al. Basal body stability and ciliogenesis requires the conserved component Poc1.