Pinin Antibodies

AND PNN ELISA kits, Pinin Proteins

Many biological assays use antibodies to detect Pinin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pinin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pinin antibodies...

We validate the specificity of these antibodies to Pinin by testing them on tissues known to express PNN positively and negatively. Browse below to find the PNN antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PNN Infographic by Boster Bio

All PNN Products

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Product

Figures

Specificity

Applications

Price

Anti-PNN/Pinin Antibody

4 Q&As

Human, Mouse

$360
Cat # A01590
100 µl

Anti-Pinin PNN Antibody

Human, Mouse, Rat

$405
Cat # A01590-1
100ul

Anti-PNN/DRSP Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A01590-2
100 μg/vial

Pinin (PNN) (NM_002687) Human Over-expression Lysate

Human

$628
Cat # LS005411
100 µg

PNN Overview

Facts about Pinin.

PNN 3D structure. Source: alphafold

Pinin (PNN)

Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression.

Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated things that join the complex only transiently either through EJC assembly or during subsequent mRNA metabolism.

Gene Information

Human
Gene Name:	PNN
Uniprot:	Q9H307
Entrez:	5411

Family

Belongs to:

pinin family

Alternative Names

140 kDa nuclear and cell adhesion-related phosphoprotein; Desmosome-associated protein; Domain-rich serine protein; DRS protein; DRSP; DRSSR-like protein; Melanoma metastasis clone A protein; memA; neutrophil protein; Nuclear protein SDK3; pinin; pinin, desmosome associated protein; SDK3

Molecular Weight

Mass (kDA):
81.628 kDA

Genomic Context


Human

Location:	14q21.1
Sequence:	14; NC_000014.9 (39175254..39183220)

Tissue Specificity

Expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon, heart, epidermis, esophagus, brain and smooth and skeletal muscle. Expressed strongly in melanoma metastasis lesions and advanced primary tumors.

Subcellular Localizations

Nucleus speckle. Cell junction, desmosome. Cell-cell contact area, predominantly desmosome of intercellular adherens junction. Not a nucleocytoplasmic shuttling protein.