PMS1 protein homolog 1 Antibodies

AND PMS1 ELISA kits, PMS1 protein homolog 1 Proteins

Many biological assays use antibodies to detect PMS1 protein homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PMS1 protein homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PMS1 protein homolog 1 antibodies...

We validate the specificity of these antibodies to PMS1 protein homolog 1 by testing them on tissues known to express PMS1 positively and negatively. Browse below to find the PMS1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PMS1 Infographic by Boster Bio

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Anti-PMS1 protein homolog 1 PMS1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A04425
100ul

Anti-PMS1 Mouse Monoclonal Antibody [Clone ID: OTI5E10]

Human

$523
Cat # M04425
100 µl

PMS1 Overview

Facts about PMS1 protein homolog 1.

PMS1 3D structure. Source: alphafold

PMS1 protein homolog 1 (PMS1)

Probably involved in the repair of mismatches in DNA.
.

Gene Information

Human
Gene Name:	PMS1
Uniprot:	P54277
Entrez:	5378

Family

Belongs to:

DNA mismatch repair MutL/HexB family

Alternative Names

DKFZp781M0253; FLJ98259; HNPCC3; hPMS1; human homolog of yeast mutL; mismatch repair gene PMSL1; PMS1 postmeiotic segregation increased 1 (S. cerevisiae); PMS1 protein homolog 1; PMSL1DNA mismatch repair protein PMS1; postmeiotic segregation increased (S. cerevisiae) 1; rhabdomyosarcoma antigen MU-RMS-40.10B; rhabdomyosarcoma antigen MU-RMS-40.10E

Molecular Weight

Mass (kDA):
105.83 kDA

Genomic Context


Human

Location:	2q32.2
Sequence:	2; NC_000002.12 (189784085..189877629)

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer
Neoplasms
Microsatellite Instability
Malignant Tumor Of Colon
Colorectal Neoplasms
Carcinoma
Endometrial Polyp
Cell Transformation, Neoplastic
Genomic Instability
Endometrial Carcinoma

Ovarian Neoplasm
Polyposis
Melanoma
Malignant Paraganglionic Neoplasm
Mutation, Out-of-frame
Malignant Neoplasm Of Breast
Aneuploidy

Pathways

Mismatch Repair
Dna Repair
Dna Replication
Gene Conversion
Meiosis
Pathogenesis
Cell Cycle
Methylation
Mitotic Recombination
Recombinational Repair
Heteroduplex Formation
Proteolysis
Double-strand Break Repair

Localization
Meiotic Gene Conversion
Dna Damage Checkpoint
S Phase
Aging
Fertilization
Immune Response

PTMs

Methylation
Phosphorylation
Cleavage

Demethylation
Reduction
Oxidation

Research Areas

DNA Repair
Mismatch Repair
Ovarian Carcinoma Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PMS1

References

PMID: 8072530 by Nicolaides N.C., et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer.

PMID: 10748105 by Leung W.K., et al. Identification of a second MutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cells.