Phosphomannomutase 2 Antibodies

AND PMM2 ELISA kits, Phosphomannomutase 2 Proteins

Many biological assays use antibodies to detect Phosphomannomutase 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Phosphomannomutase 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Phosphomannomutase 2 antibodies...

We validate the specificity of these antibodies to Phosphomannomutase 2 by testing them on tissues known to express PMM2 positively and negatively. Browse below to find the PMM2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PMM2 Infographic by Boster Bio

All PMM2 Products

Product

Figures

Specificity

Applications

Price

Anti-Phosphomannomutase 2 PMM2 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A03146
100ul

PMM2 (NM_000303) Human Recombinant Protein

$1249
Cat # PROTO15305
20 µg

Anti-PMM2 Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A03146-1
100 µg/vial

PMM2 Overview

Facts about Phosphomannomutase 2.

PMM2 3D structure. Source: alphafold

Phosphomannomutase 2 (PMM2)

Involved in the synthesis of this GDP-mannose and dolichol-phosphate-mannose necessary for a number of critical mannosyl transfer reactions. .

Gene Information

Human
Gene Name:	PMM2
Uniprot:	O15305
Entrez:	5373

Family

Belongs to:

eukaryotic PMM family

Alternative Names

CDG1; CDG1a; CDGS; EC 5.4.2.8; phosphomannomutase 2; PMM 2

Molecular Weight

Mass (kDA):
28.082 kDA

Genomic Context


Human

Location:	16p13.2
Sequence:	16; NC_000016.10 (8797813..8849326)

Subcellular Localizations

Cytoplasm.

Diseases

Congenital Disorders Of Glycosylation
Congenital Disorders
Carbohydrate-deficient Glycoprotein Syndrome Type I
Hypoplasia
Congenital Cerebellar Hypoplasia
Muscle Hypotonia
Ataxia
Atrophy
Nervousness
Metabolic Diseases
Strabismus
Hereditary Diseases

Failure To Thrive
Blood Coagulation Disorders
Pericardial Effusion
Multiple Organ Failure
Edema
Peripheral Neuropathy

Interacting Proteins

ACY3

Pathways

Glycosylation
Coagulation
Transport
Protein Glycosylation
Pathogenesis
Cell Adhesion
Blood Coagulation
Brain Development
Immune Response
Neurogenesis
Protein Transport

Virulence
Localization
Macrophage Activation
Cell Death
Mating

PTMs

Glycosylation
Phosphorylation

Cleavage
Acylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PMM2

References

PMID: 9140401 by Matthijs G., et al. Mutations in PMM2, a phosphomannomutase gene on chromosome 16p13, in carbohydrate-deficient glycoprotein type I syndrome (Jaeken syndrome).

PMID: 9425221 by Schollen E., et al. Comparative analysis of the phosphomannomutase genes PMM1, PMM2 and PMM2psi: the sequence variation in the processed pseudogene is a reflection of the mutations found in the functional gene.