PMF1 Antibodies

AND PMF1 ELISA kits, PMF1 Proteins

Many biological assays use antibodies to detect PMF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PMF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PMF1 antibodies...

We validate the specificity of these antibodies to PMF1 by testing them on tissues known to express PMF1 positively and negatively. Browse below to find the PMF1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PMF1 Infographic by Boster Bio

All PMF1 Products

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Product

Figures

Specificity

Applications

Price

Anti-PMF1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, WB

$370
Cat # M08465
100 μl/vial

PMF1 (NM_007221) Human Over-expression Lysate

Human

$628
Cat # LS011243
100 µg

PMF1 Overview

Facts about Polyamine-modulated factor 1.

PMF1 3D structure. Source: alphafold

Polyamine-modulated factor 1 (PMF1)

Part of the MIS12 complex that's required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.

Gene Information

Human
Gene Name:	PMF1
Uniprot:	Q6P1K2
Entrez:	11243

Family

Belongs to:

No superfamily

Alternative Names

PMF-1; Polyamine Modulated Factor 1

Molecular Weight

Mass (kDA):
23.339 kDA

Genomic Context


Human

Location:	1q22
Sequence:	1; NC_000001.11 (156212988..156240077)

Tissue Specificity

Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver.

Subcellular Localizations

Nucleus. Chromosome, centromere, kinetochore. Associated with the kinetochore.

Diseases

Malignant Neoplasms
Neoplasms
Bladder Neoplasm
Hypertrophic Cardiomyopathy
Tumor Progression
Malignant Neoplasm Of Breast
Von Hippel-lindau Syndrome
Aneuploidy
Malignant Neoplasm Of Urinary Bladder
Cardiomyopathies
Heart Diseases

Hypertrophy
Myeloid Leukemia
Nervousness
Leukemia
Mammary Neoplasms

Interacting Proteins

FBXO28
MIS12
TSNAX
USHBP1

Pathways

Cell Growth
Polyamine Homeostasis
Methylation
Reverse Transcription
Cell Proliferation
Cell Death
Mitosis
Kinetochore Localization

Rna Interference
Chromosome Segregation
Localization

PTMs

Demethylation

Methylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PMF1

References

PMID: 10419538 by Wang Y., et al. Cloning and characterization of human polyamine-modulated factor-1, a transcriptional cofactor that regulates the transcription of the spermidine/spermine N(1)-acetyltransferase gene.

PMID: 11256947 by Wang Y., et al. Characterization of the interaction between the transcription factors human polyamine modulated factor (PMF-1) and NF-E2-related factor 2 (Nrf-2) in the transcriptional regulation of the spermidine/spermine N1-acetyltransferase (SSAT) gene.