PLOD3 Antibodies

AND PLOD3 ELISA kits, PLOD3 Proteins

Many biological assays use antibodies to detect PLOD3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLOD3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLOD3 antibodies...

We validate the specificity of these antibodies to PLOD3 by testing them on tissues known to express PLOD3 positively and negatively. Browse below to find the PLOD3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLOD3 Infographic by Boster Bio

All PLOD3 Products

Product

Figures

Specificity

Applications

Price

Anti-PLOD3 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A06773
100ul

PLOD3 (NM_001084) Human Over-expression Lysate

Human

$628
Cat # LS008985
100 µg

PLOD3 Overview

Facts about Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3.

PLOD3 3D structure. Source: alphafold

Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3)

Multifunctional enzyme which catalyzes a collection of essential post-translational modifications on Lys residues in procollagen (PubMed:11956192, PubMed:12475640, PubMed:18298658, PubMed:30089812, PubMed:18834968). Plays a redundant role in catalyzing the transfer of galactose on hydroxylysine groups, giving rise to galactosyl 5-hydroxylysine (PubMed:12475640, PubMed:18298658, PubMed:30089812, PubMed:18834968).

Has an important role by catalyzing the subsequent transfer of sugar moieties, giving rise to 1,2-glucosylgalactosyl-5-hydroxylysine residues (PubMed:10934207, PubMed:11896059, PubMed:11956192, PubMed:12475640, PubMed:18298658, PubMed:30089812, PubMed:18834968). Catalyzes hydroxylation and glycosylation of Lys residues in the MBL1 collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues (PubMed:25419660).

Gene Information

Human
Gene Name:	PLOD3
Uniprot:	O60568
Entrez:	8985

Family

Belongs to:

No superfamily

Alternative Names

Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3

Molecular Weight

Mass (kDA):
84.785 kDA

Genomic Context


Human

Location:	7q22.1
Sequence:	7; NC_000007.14 (101205984..101217581, complement)

Tissue Specificity

Ubiquitous (PubMed:9724729). Detected in heart, placenta and pancreas, and at lower levels in lung, liver and skeletal muscle (PubMed:9582318, PubMed:9724729).

Subcellular Localizations

Rough endoplasmic reticulum. Endoplasmic reticulum lumen. Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Secreted. Secreted, extracellular space. The majority of the secreted protein is associated with the extracellular matrix.

Interacting Proteins

EFHC2
EHMT2
RAB3IP
RHOXF2

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLOD3

References

PMID: 9582318 by Valtavaara M., et al. Primary structure, tissue distribution, and chromosomal localization of a novel isoform of lysyl hydroxylase (lysyl hydroxylase 3).

PMID: 9724729 by Passoja K., et al. Cloning and characterization of a third human lysyl hydroxylase isoform.