PLCB3 Antibodies

AND PLCB3 ELISA kits, PLCB3 Proteins

Many biological assays use antibodies to detect PLCB3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLCB3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLCB3 antibodies...

We validate the specificity of these antibodies to PLCB3 by testing them on tissues known to express PLCB3 positively and negatively. Browse below to find the PLCB3 antibody that suites your experiment. We have 9 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLCB3 Infographic by Boster Bio

All PLCB3 Products

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Specificity

Applications

Price

PLCbeta3 Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$480
Cat # EKC1475
1 kit, containing one 96-well plate and all necessary reagents

PLCbeta3 (Phospho-Ser1105) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC1992
1 kit, containing two 96-well plates and all necessary reagents

PLCbeta3 (Phospho-Ser537) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2177
1 kit, containing two 96-well plates and all necessary reagents

Anti-PLC Beta 3 (D1099) PLCB3 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A04226-1
100ul

Anti-PLC Beta 3 (phospho-S537) PLCB3 Antibody

Human, Mouse, Rat

$482
Cat # A04226S537
100ul

Anti-Phospho-PLC beta (S1105) PLCB3 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A04226S1105
100ul

Anti-Phospho-PLC beta (S537) PLCB3 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A04226S537-1
100ul

Anti-PLCB3 Rabbit Monoclonal Antibody

Human

IHC, WB

$370
Cat # M04226
100 μl/vial

Anti-Phospho-PLCB3 (S537) Rabbit Monoclonal Antibody

Human

$370
Cat # M04226S537
100 µl/vial

PLCB3 Overview

Facts about 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3.

PLCB3 3D structure. Source: alphafold

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (PLCB3)

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. .

Gene Information

Human
Gene Name:	PLCB3
Uniprot:	Q01970
Entrez:	5331

Family

Belongs to:

No superfamily

Alternative Names

1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; EC 3.1.4.11; FLJ37084; Phosphoinositide phospholipase C-beta-3; phospholipase C, beta 3 (phosphatidylinositol-specific); Phospholipase C-beta-3; PLC beta 3; PLCB3; PLCbeta 3; PLC-beta 3; PLC-beta-3

Molecular Weight

Mass (kDA):
138.799 kDA

Genomic Context


Human

Location:	11q13.1
Sequence:	11; NC_000011.10 (64251530..64269452)

Subcellular Localizations

Membrane; Peripheral membrane protein.

Diseases

Neoplasms
Multiple Endocrine Neoplasia Type 1
Malignant Neoplasms
Endocrine Gland Neoplasms
Multiple Endocrine Neoplasia
Pertussis
Hypertrophy
Inflammation
Neuroblastoma
Lung Diseases
Carcinoma
Pain
Cell Transformation, Neoplastic

Leukemia
Neuroendocrine Tumors
Pituitary Diseases
Adenocarcinoma
Tissue Adhesions
Hyperplasia
Cardiac Hypertrophy

Interacting Proteins

Gnaq

Pathways

Localization
Cell Proliferation
Chemotaxis
Secretion
Translation
Cell Cycle
Mismatch Repair
Cell Growth
Transport
Cell Activation
Cell Migration
Gene Silencing
Platelet Activation

Hypersensitivity
Muscle Contraction
Endothelial Cell Proliferation
Mast Cell Activation
Inflammatory Response
Cell Maturation
Phagocytosis

PTMs

Phosphorylation

Dephosphorylation

Cleavage

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLCB3

References

PMID: 7612006 by Mazuruk K., et al. Structural organization and expression of the human phosphatidylinositol-specific phospholipase C beta-3 gene.

PMID: 7607669 by Lagercrantz J., et al. Genomic organization and complete cDNA sequence of the human phosphoinositide-specific phospholipase C beta 3 gene (PLCB3).