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- Table of Contents
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PLAUR Antibodies
AND PLAUR ELISA kits, PLAUR Proteins
Many biological assays use antibodies to detect PLAUR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLAUR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLAUR antibodies...
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PLAUR Infographic by Boster Bio
All PLAUR Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0536
96 wells/kit, with removable strips.
Cat # EK0536
96 wells/kit, with removable strips.
Mouse uPAR / uPA Receptor ELISA Kit PicoKine®
1 Citations 9 Q&As
Mouse
ELISA
$499
Cat # EK1215
96 wells/kit, with removable strips.
Cat # EK1215
96 wells/kit, with removable strips.
Anti-uPA Receptor/PLAUR Antibody Picoband®
1 Citations 6 Q&As
Human
IHC, WB
$370
Cat # PA1344
100 μg/vial
Cat # PA1344
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # A00993-3
100 μg/vial
Cat # A00993-3
100 μg/vial
Human, Mouse, Rat
ELISA, WB
$370
Cat # A00993-4
100 μg/vial
Cat # A00993-4
100 μg/vial
PLAUR Overview
Facts about Urokinase plasminogen activator surface receptor.
Urokinase plasminogen activator surface receptor (PLAUR)
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation.
Mediates the proteolysis-independent signal transduction activation effects of U-PA. It's subject to negative-feedback regulation by U-PA that cleaves it in an inactive form.
Gene Information
| Human | |
|---|---|
| Gene Name: | PLAUR |
| Uniprot: | Q03405 |
| Entrez: | 5329 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD87 antigen; CD87; Monocyte activation antigen Mo3; plasminogen activator, urokinase receptor; PLAUR; uPAR; U-PAR; UPARurokinase plasminogen activator surface receptor; u-plasminogen activator receptor form 2; URKRMO3
Molecular Weight
Mass (kDA):
36.978 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.31 |
| Sequence: | 19; NC_000019.10 (43646095..43670346, complement) |
Tissue Specificity
Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
Subcellular Localizations
Cell membrane. Cell projection, invadopodium membrane. Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin-dependent manner.; [Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 2]: Secreted.
Diseases
- Neoplasms
- Malignant Neoplasms
- Cell Invasion
- Neoplasm Metastasis
- Tissue Adhesions
- Carcinoma
- Neoplasm Invasiveness
- Mammary Neoplasms
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Tumor Angiogenesis
- Inflammation
Interacting Proteins
- ANG
- PLAU
Pathways
- Proteolysis
- Plasminogen Activation
- Cell Migration
- Angiogenesis
- Cell Adhesion
- Localization
- Cell Proliferation
- Secretion
- Fibrinolysis
- Pathogenesis
- Chemotaxis
- Cell Motility
- Tissue Remodeling
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Gpi Anchoring
- Biotinylation
- Dephosphorylation
- Iodination
- Deglycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLAUR
bosterbio.com/bosterbio-gene-info-cards/PLAUR
References
PMID: 1689240 by Roldan A.L., et al. Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis.
PMID: 1316922 by Min H.Y., et al. cDNA for Mo3, a monocyte activation antigen, encodes the human receptor for urokinase plasminogen activator.
2 Publications of Boster PLAUR Antibodies & ELISA Kits
- PubMed ID: 10.3389/fphar.2018.01016, Ulinastatin Inhibits Osteoclastogenesis and Suppresses Ovariectomy-Induced Bone ...
- PubMed ID: 10.1021/acs.jafc.8b02351, Apigenin Suppresses the IL-1β-Induced Expression of the Urokinase-Type Plasmino...
*More publications can be found for each product on its corresponding product page