This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Secretory phospholipase A2 receptor.
Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both negative and positive regulation of sPLA2 functions in addition to clearance of sPLA2.
Mouse | |
---|---|
Gene Name: | Pla2r1 |
Uniprot: | Q62028 |
Entrez: | 18779 |
Belongs to: |
---|
No superfamily |
180 kDa secretory phospholipase A2 receptor; CLEC13C; CLEC13CC-type lectin domain family 13 member C; phospholipase A2 receptor 1, 180kDa; PLA2G1R; PLA2IR; PLA2R1; PLA2-RM-type receptor; PLA2Rphospholipase A2 receptor 1, 180kD; secretory phospholipase A2 receptor
Mass (kDA):
170.512 kDA
Mouse | |
---|---|
Location: | 2|2 C1.1-C1.2 |
Sequence: | 2; |
Widely expressed. Present in type II alveolar epithelial cells and a subset of splenic lymphocytes. Present at the surface of polymorphonuclear neutrophils (at protein level).
PMID: 7925459 by Higashino K., et al. Structural comparison of phospholipase-A2-binding regions in phospholipase-A2 receptors from various mammals.
PMID: 9407054 by Hanasaki K., et al. Resistance to endotoxic shock in phospholipase A2 receptor-deficient mice.