PLA2G2A Antibodies

AND PLA2G2A ELISA kits, PLA2G2A Proteins

Many biological assays use antibodies to detect PLA2G2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLA2G2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLA2G2A antibodies...

We validate the specificity of these antibodies to PLA2G2A by testing them on tissues known to express PLA2G2A positively and negatively. Browse below to find the PLA2G2A antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLA2G2A Infographic by Boster Bio

All PLA2G2A Products

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Specificity

Applications

Price

Human PLA2G2A ELISA Kit PicoKine®

5 Q&As

Human

ELISA

$499
Cat # EK1944
96 wells/kit, with removable strips.

Mouse PLA2G2A ELISA Kit PicoKine®

1 Citations 8 Q&As

Mouse

ELISA

$499
Cat # EK1945
96 wells/kit, with removable strips.

Anti-PLA2G2A Antibody

Human, Mouse

$405
Cat # A02259
100ul

Anti-Phospholipase A2 IIA (PLA2G2A) Mouse Monoclonal Antibody [Clone ID: OTI1C2]

Human

$523
Cat # M02259
100 µl

Anti-PLA2G2A Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M02259-1
100 μl/vial

PLA2G2A Overview

Facts about Phospholipase A2, membrane associated.

PLA2G2A 3D structure. Source: alphafold

Phospholipase A2, membrane associated (PLA2G2A)

Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis.

Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877).

Gene Information

Human
Gene Name:	PLA2G2A
Uniprot:	P14555
Entrez:	5320

Family

Belongs to:

phospholipase A2 family

Alternative Names

EC 3.1.1.4; GIIC sPLA2; Group IIA phospholipase A2; Mom1; Non-pancreatic secretory phospholipase A2; NPS-PLA2; Phosphatidylcholine 2-acylhydrolase 2A; phospholipase A2, group IIA (platelets, synovial fluid); phospholipase A2, membrane associated; PLA2B; PLA2BPLA2; PLA2G2A; PLA2L; PLA2LPLA2S; PLAS1; RASF-A; sPLA2

Molecular Weight

Mass (kDA):
16.083 kDA

Genomic Context


Human

Location:	1p36.13
Sequence:	1; NC_000001.11 (19975431..19980434, complement)

Subcellular Localizations

Cell membrane; Peripheral membrane protein. Secreted.

Diseases

Neoplasms
Malignant Neoplasms
Inflammation
Cell Transformation, Neoplastic
Adenoma
Intestinal Neoplasms
Polyposis
Adenomatous Polyposis Coli
Colorectal Cancer
Carcinoma
Colorectal Neoplasms
Colonic Neoplasms
Carcinogenesis

Adenocarcinoma
Malignant Tumor Of Colon
Polyps
Atherosclerosis
Stomach Neoplasms
Diabetes Mellitus
Malignant Neoplasm Of Stomach

Interacting Proteins

ITGB3

Pathways

Cell Proliferation
Pathogenesis
Localization
Immune Response
Inflammatory Response
Cell Differentiation
Dna Repair
Cell Growth
Secretion
Cell Cycle
Macropinocytosis
Autophagy
Keratinization

Osteoclast Differentiation
Cell Activation
Cell Migration
Dna Hypermethylation
Gene Silencing
B Cell Activation
Chondrocyte Differentiation

PTMs

Phosphorylation
Cleavage

Oxidation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLA2G2A

References

PMID: 2925608 by Seilhamer J.J., et al. Cloning and recombinant expression of phospholipase A2 present in rheumatoid arthritic synovial fluid.

PMID: 2925633 by Kramer R.M., et al. Structure and properties of a human non-pancreatic phospholipase A2.

1 Publications of Boster PLA2G2A Antibodies & ELISA Kits

PubMed ID: 10.1016/j.jep.2020.112641, Moslea Herba flavonoids alleviated influenza A virus-induced pulmonary endotheli...

*More publications can be found for each product on its corresponding product page