Group XV phospholipase A2 Antibodies

AND PLA2G15 ELISA kits, Group XV phospholipase A2 Proteins

Many biological assays use antibodies to detect Group XV phospholipase A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Group XV phospholipase A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Group XV phospholipase A2 antibodies...

We validate the specificity of these antibodies to Group XV phospholipase A2 by testing them on tissues known to express PLA2G15 positively and negatively. Browse below to find the PLA2G15 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: ZKSCAN5

PLA2G15 Infographic by Boster Bio

All PLA2G15 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

LYPLA3 (PLA2G15) (NM_012320) Human Over-expression Lysate

Human

$628
Cat # LS023659
100 µg

Anti-LYPLA3/PLA2G15 Antibody Picoband®

Human

ELISA, IF, ICC, WB

$370
Cat # A08649
100 µg/vial

PLA2G15 Overview

Facts about Group XV phospholipase A2.

PLA2G15 3D structure. Source: alphafold

Group XV phospholipase A2 (PLA2G15)

Has transacylase and calcium-independent phospholipase A2 activity (PubMed:20410020, PubMed:23958596). Catalyzes the formation of 1-O-acyl-N-acetylsphingosine and the concomitant release of a lyso-phospholipid (PubMed:11790796, PubMed:25727495).

Has high activity with 1-palmitoyl-2-oleoyl-sn-glycero-3- phosphocholine (POPC) and 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC), catalyzing the transfer of oleic acid to N-acetyl- sphingosine. Required for normal phospholipid degradation in alveolar and peritoneal macrophages and in spleen (By similarity).

Gene Information

Human
Gene Name:	PLA2G15
Uniprot:	Q8NCC3
Entrez:	23659

Family

Belongs to:

AB hydrolase superfamily

Alternative Names

1-O-acylceramide synthase; ACSDKFZp564A0122; EC 2.3.1.43; GXVPLA2; LLPLLCAT-like lysophospholipase; LPLA2group XV phospholipase A2; LYPLA3EC 2.3.1.-; lysophospholipase 3 (lysosomal phospholipase A2); Lysophospholipase 3; Lysosomal phospholipase A2; phospholipase A2, group XV

Molecular Weight

Mass (kDA):
46.658 kDA

Genomic Context


Human

Location:	16q22.1
Sequence:	16; NC_000016.10 (68245371..68261062)

Tissue Specificity

Detected in blood plasma (at protein level) (PubMed:10092508, PubMed:20410020). Ubiquitous. Highly expressed in heart, placenta, skeletal muscle, kidney and pancreas. Detected at lower levels in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes (PubMed:10092508).

Subcellular Localizations

Lysosome. Secreted. Membrane; Peripheral membrane protein.

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLA2G15

References

PMID: 10092508 by Taniyama Y., et al. Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.

PMID: 11790796 by Hiraoka M., et al. Cloning and characterization of a lysosomal phospholipase A2, 1-O- acylceramide synthase.