PKN2 Antibodies

AND PKN2 ELISA kits, PKN2 Proteins

Many biological assays use antibodies to detect PKN2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PKN2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PKN2 antibodies...

We validate the specificity of these antibodies to PKN2 by testing them on tissues known to express PKN2 positively and negatively. Browse below to find the PKN2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PKN2 Infographic by Boster Bio

All PKN2 Products

Product

Figures

Specificity

Applications

Price

Anti-PRK2 PKN2 Monoclonal Antibody

Human, Monkey, Mouse, Rat

Flow Cytometry, IHC, WB

$399
Cat # A04066
100μl

Anti-PKN2/Prk2 Rabbit Monoclonal Antibody

5 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M04066
100 μl

Anti-PKN2 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # M04066-1
100 μl/vial

PKN2 (NM_006256) Human Over-expression Lysate

Human

$960
Cat # LS005586
100 µg

PKN2 Overview

Facts about Serine/threonine-protein kinase N2.

PKN2 3D structure. Source: alphafold

Serine/threonine-protein kinase N2 (PKN2)

PKC-related serine/threonine-protein kinase and Rho/Rac effector protein which participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling procedures.

Phosphorylates CTTN in hyaluronan-induced astrocytes and thus decreases CTTN ability to connect with filamentous actin. Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells.

Gene Information

Human
Gene Name:	PKN2
Uniprot:	Q16513
Entrez:	5586

Family

Belongs to:

protein kinase superfamily

Alternative Names

cardiolipin-activated protein kinase Pak2; EC 2.7.11; EC 2.7.11.13; PAK2; Pak-2; PKN2; PRK2; PRK2MGC150606; PRKCL2; PRKCL2PRO2042; PRO2042; Protein kinase C-like 2MGC71074; protein kinase N2; Protein-kinase C-related kinase 2; serine/threonine-protein kinase N2

Molecular Weight

Mass (kDA):
112.035 kDA

Genomic Context


Human

Location:	1p22.2
Sequence:	1; NC_000001.11 (88684144..88836255)

Tissue Specificity

Ubiquitous. Expressed in numerous tumor cell lines, especially in bladder tumor cells.

Subcellular Localizations

Cytoplasm. Nucleus. Membrane. Cell projection, lamellipodium. Cytoplasm, cytoskeleton. Cleavage furrow. Midbody. Cell junction. Colocalizes with PTPN13 in lamellipodia-like structures, regions of large actin turnover. Accumulates during telophase at the cleavage furrow and concentrates finally around the midbody in cytokinesis. Recruited to nascent cell-cell contacts at the apical surface of cells. In the course of viral infection, colocalizes with HCV NS5B at perinuclear region in the cytoplasm.