Pyruvate kinase PKLR Antibodies

AND PKLR ELISA kits, Pyruvate kinase PKLR Proteins

Many biological assays use antibodies to detect Pyruvate kinase PKLR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pyruvate kinase PKLR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pyruvate kinase PKLR antibodies...

We validate the specificity of these antibodies to Pyruvate kinase PKLR by testing them on tissues known to express PKLR positively and negatively. Browse below to find the PKLR antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PKLR Infographic by Boster Bio

All PKLR Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PKLR Antibody Picoband®

1 Citations 1 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # PB9499
100 μg/vial

Human PKLR Recombinant Protein

Enzyme Activity, SDS-PAGE

$265
Cat # PROTP30613
Starting from 10ug

Anti-Pyruvate Kinase (PKLR) Mouse Monoclonal Antibody [Clone ID: OTI1H4]

Human, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M02282
100 µl

Pyruvate Kinase (PKLR) (NM_000298) Human Over-expression Lysate

Human

$628
Cat # LS005313
100 µg

Human PKLR ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2257
96 wells/kit, with removable strips.

PKLR Overview

Facts about Pyruvate kinase PKLR.

PKLR 3D structure. Source: alphafold

Pyruvate kinase PKLR (PKLR)

Plays a crucial role in glycolysis. .

Gene Information

Human
Gene Name:	PKLR
Uniprot:	P30613
Entrez:	5313

Family

Belongs to:

pyruvate kinase family

Alternative Names

EC 2.7.1.40; PK1; PK1PKRL; PKL; PKLR; PKR; Pyruvate Kinase 1; pyruvate kinase isozyme R/L; pyruvate kinase isozymes R/L; pyruvate kinase type L; pyruvate kinase, liver and blood cell; pyruvate kinase, liver and RBC; Red cell/liver pyruvate kinase; RPK; R-type/L-type pyruvate kinase

Molecular Weight

Mass (kDA):
61.83 kDA

Genomic Context


Human

Location:	1q22
Sequence:	1; NC_000001.11 (155289293..155301438, complement)

Diseases

Pyruvate Kinase Deficiency
Anemia
Anemia, Hemolytic
Malaria
Anemia, Hemolytic, Congenital Nonspherocytic
Dysequilibrium Syndrome
Gaucher Disease
Diabetes Mellitus
Parasitemia
Diabetes Mellitus, Non-insulin-dependent
Inborn Errors Of Metabolism
Anemia, Hemolytic, Congenital

Hypoxia
Carcinoma
Hereditary Diseases
Acute Erythroblastic Leukemia
Icterus
Hemoglobinopathies
Cell Invasion

Pathways

Secretion
Insulin Secretion
Localization
Glycolysis
Transport
Regulation Of Macroautophagy
Cell Proliferation
Cellular Homeostasis
Dna Methylation
Regulation Of Gene Expression
Oxidative Phosphorylation
Methylation
Disease Resistance

Drug Resistance
Reverse Transcription
Lactate Transport
Macroautophagy
Phagocytosis
Cell Differentiation
Histone Acetylation

PTMs

Acetylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PKLR

References

PMID: 1896471 by Kanno H., et al. cDNA cloning of human R-type pyruvate kinase and identification of a single amino acid substitution (Thr384-->Met) affecting enzymatic stability in a pyruvate kinase variant (PK Tokyo) associated with hereditary hemolytic anemia.

PMID: 3126495 by Tani K., et al. Human liver type pyruvate kinase: complete amino acid sequence and the expression in mammalian cells.

1 Publications of Boster Pyruvate kinase PKLR Antibodies & ELISA Kits

PubMed ID: 10.1111/jcmm.13805, miR‐1322 regulates ChREBP expression via binding a 3′‐UTR variant (rs10519...

*More publications can be found for each product on its corresponding product page