PIK3C2B Antibodies

AND PIK3C2B ELISA kits, PIK3C2B Proteins

Many biological assays use antibodies to detect PIK3C2B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PIK3C2B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PIK3C2B antibodies...

We validate the specificity of these antibodies to PIK3C2B by testing them on tissues known to express PIK3C2B positively and negatively. Browse below to find the PIK3C2B antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PIK3C2B Infographic by Boster Bio

All PIK3C2B Products

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Specificity

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Price

Anti-P3C2B PIK3C2B Antibody

Human

ELISA, WB

$380
Cat # A06732
100ul

PIK3C2B (NM_002646) Human Recombinant Protein

$1062
Cat # PROTO00750
20 µg

Anti-PIK3C2B Mouse Monoclonal Antibody [Clone ID: OTI2G3]

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M06732
100 µl

Anti-PIK3C2B Mouse Monoclonal Antibody [Clone ID: OTI3B1]

Human, Mouse, Rat

IHC, WB

$523
Cat # M06732-1
100 µl

PIK3C2B (NM_002646) Human Over-expression Lysate

Human

$960
Cat # LS005287
100 µg

PIK3C2B Overview

Facts about Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta.

PIK3C2B 3D structure. Source: alphafold

Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PIK3C2B)

Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns.
Does not phosphorylate PtdIns(4,5)P2.

May be involved in EGF and PDGF signaling cascades. .

Gene Information

Human
Gene Name:	PIK3C2B
Uniprot:	O00750
Entrez:	5287

Family

Belongs to:

PI3/PI4-kinase family

Alternative Names

C2-PI3K; C2-PI3KDKFZp686G16234; EC 2.7.1; EC 2.7.1.154; phosphatidylinositol 3-kinase C2 domain-containing beta polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta; Phosphoinositide 3-kinase-C2-beta; phosphoinositide-3-kinase, class 2, beta polypeptide; PI 3Kinase C2 beta; PI 3-Kinase C2 beta; PI3K-C2beta; PI3K-C2-beta; PIK3C2B; PTDINS-3-kinase C2 beta; PtdIns-3-kinase C2 subunit beta

Molecular Weight

Mass (kDA):
184.768 kDA

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (204422633..204494815, complement)

Tissue Specificity

Expressed in columnar and transitional epithelia, mononuclear cells, and ganglion cells (at protein level). Widely expressed, with highest levels in thymus and placenta and lowest in peripheral blood, skeletal muscle and kidney.

Subcellular Localizations

Microsome. Cell membrane. Cytoplasm, cytosol. Nucleus. Endoplasmic reticulum. Found mostly in the microsome, but also in the plasma membrane and cytosol. Nuclear in testis.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Glioblastoma
Brain Neoplasms
Malignant Squamous Cell Neoplasm
Glioma
Malignant Paraganglionic Neoplasm
Glioblastoma Multiforme
Hyperplasia
Sclerosis
Neoplasm Metastasis
Mutation Abnormality

Malignant Neoplasm Of Brain
Protein Deficiency
Diffuse Scleroderma
Myopathy
Lupus Erythematosus, Systemic
Epithelial Ovarian Cancer
Ovarian Neoplasm

Interacting Proteins

EGFR
ERBB2
GRB2
NCK1
TRIM27

YWHAZ

Pathways

Cell Migration
Pathogenesis
Cell Proliferation
Localization
Drug Resistance
Rna Interference
Transport
Cell Adhesion
Vesicle Transport
Proteolysis
Cd40 Signaling Pathway
Muscle Atrophy
Regeneration

Mismatch Repair
Flight
Chemotaxis
Cell Death
Cell Cycle
Cell Motility
Anoikis

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PIK3C2B

References

PMID: 9144573 by Brown R.A., et al. Identification and cDNA cloning of a novel mammalian C2 domain- containing phosphoinositide 3-kinase, HsC2-PI3K.

PMID: 9830063 by Arcaro A., et al. Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity.